New quinazolin-2,4-dione derivatives incorporating acylthiourea, pyrazole and/or oxazole moieties as antibacterial agents <i>via</i> DNA gyrase inhibition

Ibrahim, Amal O. A.; Hassan, Abdelfattah; Mosallam, Ahmed M.; Khodairy, Ahmed; Rashdan, Huda R. M.; Abdelmonsef, Aboubakr H.

doi:10.1039/d4ra02960g

RSC Adv.

2024

DOI: 10.1039/d4ra02960g

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New quinazolin-2,4-dione derivatives incorporating acylthiourea, pyrazole and/or oxazole moieties as antibacterial agents via DNA gyrase inhibition

Amal O. A. Ibrahim,

Abdelfattah Hassan,

Ahmed M. Mosallam

et al.

Abstract: Rationale design of new quinazolindione-clubbed pyrazole and/or oxazole hybrids.

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Cited by 3 publications

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Synthesis, characterization, computer-aided docking studies, and anti-fungal activity of two-armed quinazolin-2,4‑dione derivatives

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et al. 2024

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New quinazolin-2,4-dione derivatives incorporating acylthiourea, pyrazole and/or oxazole moieties as antibacterial agents via DNA gyrase inhibition

Abstract: Rationale design of new quinazolindione-clubbed pyrazole and/or oxazole hybrids.

Cited by 3 publications

References 27 publications

Novel pyrazoline-thiazole hybrids containing azo group as antibacterial agents: design, synthesis, in vitro bioactivity, in silico molecular docking, ADME profile and DFT studies

Novel pyrazoline-thiazole hybrids containing azo group as antibacterial agents: design, synthesis, in vitro bioactivity, in silico molecular docking, ADME profile and DFT studies

New 1,3-diphenyl-1H-pyrazol-5-ols as anti-methicillin resistant Staphylococcus aureus agents: Synthesis, antimicrobial evaluation and in silico studies

Synthesis, characterization, computer-aided docking studies, and anti-fungal activity of two-armed quinazolin-2,4‑dione derivatives

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