New Progress in the Design, Synthesis and Application of Fluorescent Probes for Fluoride Ion Detection

Abstract

The recognition and detection of trace fluoride ions in vivo and vitro have attracted great attention in recent years. More and more new fluorescent probes (FP) for fluoride ion detection have been designed and synthesized due to their advantages, such as high sensitivity, good selectivity and convenient operation. According to the different structural features and recognition mechanism, fluoride ion FP can be classified into two categories as deprotonation and reaction type. The new progress especially in recent three years on their molecular design, synthesis and application is reviewed on the viewpoint of green chemistry. The future trend of fluoride ion FP is also prospected.

Research Progress of Organic Polymer Fluorescence Sensor

“…例如, 何庆国课题组 [55] 近年来, 生物体内外微量氟离子的识别与检测受到 了越来越多的关注 [56] . 其中, 基于氢键作用, 设计氟离 子荧光探针受到重视 [57] . 例如, 薛善锋课题组 [58] 此外, 利用 Suzuki 偶联反应所合成的有机荧光聚合 物, 也可被设计成为各种生物传感器(图 3).…”

Recent Progress in Metal–Organic Framework (MOF) Based Luminescent Chemodosimeters

“…Various analytical techniques have been developed for sensing fluoride [130], including the well-established electrochemical method [131,132], chromatography [133,134], and colorimetric and fluorogenic assays [135]. In the past decades, numerous fluorescent probes have been developed for fluoride based on different fluoride-participated processes, such as fluoride-induced Si−O or Si−C bond cleavage, H−F hydrogen bonding formation, and Lewis acid−base interactions [136,137,138]. By exploiting these special reactivities of fluoride, several MOF-based luminesscent probes have recently been developed for its detection [139,140].…”