New Prenylated ortho‐Dihydroxycoumarins from the Fruits of Ficus nipponica

Abstract

Two new prenylated ortho-dihydroxycoumarins, designated fipsomin (1) and fipsotwin (2), were isolated from the fruits of Ficus nipponica together with a known prenylated coumarin, apigravin (3). Their structures were established by spectroscopic data and X-ray crystallographic analysis. Compound 1 exhibited antibacterial activity against Bacillus subtilis with an MIC value of 61 μm, while 2 and 3 showed very weak activity.

In Situ Study of Metabolic Response of Arabidopsis thaliana Leaves to Salt Stress by Neutral Desorption-Extractive Electrospray Ionization Mass Spectrometry

“…Apigravin was a known prenylated coumarin, which can be found in plants and belongs to the class of organic compounds known as 7-hydroxycoumarins, that contain one or more hydroxyl groups attached to the C7 position the coumarin skeleton. 22 β-Cotonefuran is one of the dibenzofurans, which are phytoalexins and produced by plants in response to biotic and abiotic stress factors. 23 Except for very high salinity stress (300 mM), the content of amino acid detected generally showed an increasing trend with salt concentration and stress duration (Figure 6), which was consistent with an earlier report.…”

“…In this study, m / z 261 (apigravin) and m / z 305 (β-cotonefuran) were identified by secondary fingerprint spectra. Apigravin was a known prenylated coumarin, which can be found in plants and belongs to the class of organic compounds known as 7-hydroxycoumarins, that contain one or more hydroxyl groups attached to the C7 position the coumarin skeleton . β-Cotonefuran is one of the dibenzofurans, which are phytoalexins and produced by plants in response to biotic and abiotic stress factors …”