Results: Total polyp grade in PNS-CT of UPG was higher than APG (p<0.05). There was no significant difference in Plt, Neu %, Lym %, Eos %, ELR of APG, UPG, and CSG (p>0.05). RDW in CSG was lower than APG and UPG (p<0.05), and it showed no significant difference between APG and UPG (p>0.05). Conclusion: Extent of unilateral sinonasal polypoid disease does not affect the severity of systemic inflammation. The effects of antrochoanal polyps on systemic inflammation are similar to the effects of unilateral sinonasal polyps.