New Polyunsaturated Amino Ketones from a Guangxi Sponge <i>Haliclona</i> sp.

Sun, Jian; Yao, Li‐Gong; Chen, Kaoshan; Liu, Haili; Xin, Guorong; Guo, Yue‐Wei

doi:10.1002/hlca.200900357

Cited by 7 publications

(4 citation statements)

References 13 publications

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“…The glycolipid sarcotride D 487 was reported from Sarcotragus sp. (Cheju Is., S. Korea), 433 while a polyunsaturated aminoketone reported from a Haliclona sponge 434 was synthesised. 435 Twelve brominated acetylenic acids xestospongienol A-L 488-499 were isolated from Xestospongia testudinaria (Hainan Is., China), 436 while another individual of the same species (Weizhou Is., South China Sea), yielded a further 39 brominated lipids xestospongiene A-Z 500-525 and Z 1 -Z 13 526-538.…”

Section: Spongesmentioning

confidence: 99%

Marine natural products

et al. 2013

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This review covers the literature published in 2011 for marine natural products, with 870 citations (558 for the period January to December 2011) referring to compounds isolated from marine microorganisms and phytoplankton, green, brown and red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves and other intertidal plants and microorganisms. The emphasis is on new compounds (1152 for 2011), together with the relevant biological activities, source organisms and country of origin. Biosynthetic studies, first syntheses, and syntheses that lead to the revision of structures or stereochemistries, have been included.

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Section: Spongesmentioning

confidence: 99%

Marine natural products

et al. 2013

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“…(Weizhou Is., Guangxi, China). 481 The synthesis of two PPAR-agonist lactones, originally isolated from Plakortis nigra, 482 has been achieved. 483 The absolute configuration of the cytotoxic oxylipin topsentolide A 1 401 (Topsentia sp.)…”

Section: Spongesmentioning

confidence: 99%

Marine natural products

et al. 2012

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Covering: 2010. Previous review: Nat. Prod. Rep., 2011, 28, 196. This review covers the literature published in 2010 for marine natural products, with 895 citations (590 for the period January to December 2010) referring to compounds isolated from marine microorganisms and phytoplankton, green, brown and red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves and other intertidal plants and microorganisms. The emphasis is on new compounds (1003 for 2010), together with the relevant biological activities, source organisms and country of origin. Biosynthetic studies, first syntheses, and syntheses that lead to the revision of structures or stereochemistries, have been included.

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“…Two new uncommon polyunsaturated amino ketones, (6 Z ,9 Z ,12 Z ,15 Z )-1-[(2-phenylethyl) amino] octadeca-6,9,12,15-tetraen-3-one ( 419 ) and (6 Z ,9 Z ,12 Z ,15 Z )-1-(diethylamino) octadeca-6,9,12,15-tetraen-3-one ( 420 ), were isolated from the Guangxi Autonomous Region sponge Haliclona sp. [ 122 ].…”

Section: New Mnps From the Beibu Gulfmentioning

confidence: 99%

Marine Natural Products from the Beibu Gulf: Sources, Chemistry, and Bioactivities

et al. 2023

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Marine natural products (MNPs) play an important role in the discovery and development of new drugs. The Beibu Gulf of South China Sea harbors four representative marine ecosystems, including coral reefs, mangroves, seaweed beds, and coastal wetlands, which are rich in underexplored marine biological resources that produce a plethora of diversified MNPs. In our ongoing efforts to discover novel and biologically active MNPs from the Beibu Gulf, we provide a systematic overview of the sources, chemical structures, and bioactive properties of a total of 477 new MNPs derived from the Beibu Gulf, citing 133 references and covering the literature from the first report in November 2003 up to September 2022. These reviewed MNPs were structurally classified into polyketides (43%), terpenoids (40%), nitrogen-containing compounds (12%), and glucosides (5%), which mainly originated from microorganisms (52%) and macroorganisms (48%). Notably, they were predominantly found with cytotoxic, antibacterial, and anti-inflammatory activities. This review will shed light on these untapped Beibu Gulf-derived MNPs as promising lead compounds for the development of new drugs.

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New Polyunsaturated Amino Ketones from a Guangxi Sponge Haliclona sp.

Cited by 7 publications

References 13 publications

Marine natural products

Marine natural products

Marine natural products

Marine Natural Products from the Beibu Gulf: Sources, Chemistry, and Bioactivities

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