New platinum(II) complexes of cycloalkanespiro-5-(2-thiohydantoins). Synthesis and quantum chemical investigation

Abstract

Synthesis and characterization of new Pt(II) complexes of cyclohexanespiro-5-(2-thiohydantoin) (L1) and cycloheptanespiro-5-(2-thiohydantoin) (L2) are discussed. The new complexes are studied by elemental analysis, IR and 1 H NMR spectroscopy. The free ligands are investigated by UV-Vis, IR, 1 H NMR, 13 C NMR and Raman spectroscopy. The ground-state equilibrium geometries of the ligands L1 and L2 and their complexes with Pt(II) are optimized at the BLYP/CEP-31G theoretical level.

Study on the Synthesis, Characterization and Bioactivities of 3-Methyl-9’-fluorenespiro-5-hydantoin

“…59 Recently, we discussed the synthesis, characterization and quantum chemical investigation of new Pt(II) complexes of cyclohexanespiro-5-(2-thiohydantoin) and cycloheptanespiro-5-(2-thiohydantoin). 63 In our previous works we reported a method for synthesis, cytotoxicity and antibacterial activity of 3-amino-9'-fluorenespiro-5-hydantoin. 61 On the other hand, compounds containing fluorene ring have been proved as organic light emitting diodes (OLED) having application in the practice.…”