New Pig Disease in Hungary: Postweaning Multisystemic Wasting Syndrome Caused by Circovirus (Short Communication)

Abstract

Postweaning multisystemic wasting syndrome (PMWS), a new disease in Hungary, was recognized in a swine herd located in Southeast Hungary, during the early winter of 1999. The first clinical signs of paleness, anaemia, and leanness appeared immediately after weaning, at the age of 40-50 days. Pustules were frequently observed on the skin of the trunk, and signs of necrotic dermatitis were also visible. A syndrome of poor growth and wasting was characteristic of the affected pigs. A porcine circovirus (PCV), the suspected causative agent, was detected by polymerase chain reaction (PCR). Sequencing data and restriction endonuclease (RE) analysis of the PCR products suggested that the virus belonged to the PCV-II group where all the causative agents of PMWS are also grouped.

Postweaning multisystemic wasting syndrome (pmws) in pigs in Croatia: Detection and characterisation of porcine circovirus type 2 (pcv2)

“…The division between 'early' and 'late stage of disease' is rather artificial, but it allowed us to discriminate those pigs that died of PMWS after a very short period of weakness in still good body condition, as described before (Dán et al, 2003), from PMWS cases of a longer clinical evolution that resulted in a clinical condition of wasting. Morbidity and mortality rates on all the eight farms monitored in this study were relatively similar to those observed in other countries where PMWS has been diagnosed (Madec et al, 2000;Kiss et al, 2000;Schmoll et al, 2002).…”

“…In Europe, PMWS was first reported from France (LeCann et al, 1997) and Spain (Segalés et al, 1997). In addition, the syndrome has also been recognised in countries neighbouring Croatia, such as Slovenia (Toplak et al, 2002), Hungary (Kiss et al, 2000), Austria (Schmoll et al, 2002) and Italy (Martelli et al, 2000).…”

Occurrence of porcine dermatitis and nephropathy syndrome in Hungary

“…The nucleotide sequence of a PCV-2 virus strain detected from a case of postweaning multisystemic wasting syndrome (PMWS) occurring in a Southern Hungarian pig herd (Kiss et al, 2000) was compared with that of the virus strain found by us. In the 451 base pair long nucleotide sequences nucleotide difference occurred in three places, two of which involved amino acid change.…”

Vascular lesions and pneumonia in a pig fetus infected by porcine circovirus type 2

“…PCV2 infection associated with PMWS was first detected in Hungary in 1999 (Kiss et al, 2000). The infection was later found to be associated with PDNS (Molnár et al, 2002) as well as PRDC (Szeredi et al, 2013).…”