New phenolic compounds from the twigs of Artocarpus heterophyllus

Di, Xiaxia; Wang, Shuqi; Wang, Bo; Liu, Yongqing; Yuan, Huipin; Lou, Hongxiang; Wang, X.

doi:10.5582/ddt.2013.v7.1.24

Cited by 16 publications

(7 citation statements)

References 22 publications

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“…Recently, two new chalcones, artocarpusins A and B; one new flavone, artocarpusin C; one new 2-arylbenzofuran derivative, artocarstilene A, were isolated from the twigs of the plant [64]. Artocarpesin has been found to reduce obesity associated inflammation by suppressing production of nitric oxide and prostaglandin E2 in macrophage cells [65].…”

Section: The Renaissance Of Food Plants As Therapeutic Agentsmentioning

confidence: 99%

“…Artocarpin has the ability to reduce cell viability in dose-dependent manner, causes alteration in cell morphology, and induces apoptosis of T47D breast cancer cells [55]. Gemichalcones A and artocarpin were presented to have moderate inhibitory activity on the proliferation of the PC-3 and H460 cell line [64]. Methanol extract of A. heterophyllus has likewise been showed to be nontoxic to normal cells (HEK293) but toxic to tA549 cell line as determined by MTT and SRB cytotoxic assays [66].…”

Section: The Renaissance Of Food Plants As Therapeutic Agentsmentioning

confidence: 99%

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The Therapeutic Potential of Medicinal Foods

Ramalingum

Mahomoodally

2014

Advances in Pharmacological Sciences

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Pharmaceutical and nutritional sciences have recently witnessed a bloom in the scientific literature geared towards the use of food plants for their diversified health benefits and potential clinical applications. Health professionals now recognize that a synergism of drug therapy and nutrition might confer optimum outcomes in the fight against diseases. The prophylactic benefits of food plants are being investigated for potential use as novel medicinal remedies due to the presence of pharmacologically active compounds. Although the availability of scientific data is rapidly growing, there is still a paucity of updated compilation of data and concerns about the rationale of these health-foods still persist in the literature. This paper attempts to congregate the nutritional value, phytochemical composition, traditional uses, in vitro and in vivo studies of 10 common medicinal food plants used against chronic noncommunicable and infectious diseases. Food plants included were based on the criteria that they are consumed as a common food in a typical diet as either fruit or vegetable for their nutritive value but have also other parts which are in common use in folk medicine. The potential challenges of incorporating these medicinal foods in the diet which offers prospective opportunities for future drug development are also discussed.

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Section: The Renaissance Of Food Plants As Therapeutic Agentsmentioning

confidence: 99%

Section: The Renaissance Of Food Plants As Therapeutic Agentsmentioning

confidence: 99%

The Therapeutic Potential of Medicinal Foods

Ramalingum

Mahomoodally

2014

Advances in Pharmacological Sciences

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“…In India, it is also called “Panasa”, “Atibruhatphala”, “Kantaphal”, and “Kanthal” due to its physical characteristics. The AH tree is also considered to be a source of flavonoids, sterols, volatile acids, carotenoids, and tannins, which vary depending on the stage of maturity [ 6 , 7 , 8 , 9 , 10 ]. Moreover, it also has a unique combination of iron, vitamin C, vitamin B complex (especially vitamin B 6 , niacin, folic acid, and riboflavin), and minerals (mainly calcium and potassium) [ 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Artocarpus lakoocha Roxb. and Artocarpus heterophyllus Lam. Flowers: New Sources of Bioactive Compounds

Gupta

Rather

Jha

et al. 2020

Plants

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Artocarpus heterophyllus Lam. (AH) and Artocarpus lakoocha Roxb. (AL) are two endemic plants that grow on the Asian continent. To date, their applications have been aimed at using their fruit as a food source or for some of their therapeutic virtues. In this study, attention was given to the flowers of AH and AL. Initially, the cytotoxicity of the phytoextracts was assessed, and the content of minerals, phenols, and flavonoids was determined. Furthermore, some antioxidant components were identified by HPLC. Furthermore, the ability of AH and AL extracts to modulate the gene expression of some targets involved in the antioxidant response was studied. The results obtained highlighted the nutritional and antioxidant value of the AH and AL flower extracts. This study will contribute to enhancing the use of AH and AL flowers as potential supplements in human nutrition.

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“…1). The known compounds were identified as moracin I (5), 11) 6-prenylapigenin (6), 12) artocarpesin (7), 12) artocarpusin C (8), 13) morachalcone A (9) 14) by analysis of their spectroscopic data and comparison with literature data.…”

Section: Resultsmentioning

confidence: 99%

Artopithecins A–D, Prenylated 2-Arylbenzofurans from the Twigs of <i>Artocarpus pithecogallus</i> and Their Tyrosinase Inhibitory Activities

Wang

Liu

et al. 2018

Chem. Pharm. Bull.

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Four new prenylated 2-arylbenzofurans, namely artopithecins AD (1-4), together with five known compounds (5-9) were isolated from the twigs of Artocarpus pithecogallus for the first time. Their structures were elucidated based on extensive spectroscopic analysis and in comparison with literature data. All isolates were evaluated for their inhibitory activities against mushroom tyrosinase. Compounds 3 and 4 displayed significant tyrosinase inhibitory activities with IC 50 values of 37.09 0.33 and 38.14 0.21 µM, respectively.

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New phenolic compounds from the twigs of Artocarpus heterophyllus

Cited by 16 publications

References 22 publications

The Therapeutic Potential of Medicinal Foods

The Therapeutic Potential of Medicinal Foods

Artocarpus lakoocha Roxb. and Artocarpus heterophyllus Lam. Flowers: New Sources of Bioactive Compounds

Artopithecins A–D, Prenylated 2-Arylbenzofurans from the Twigs of <i>Artocarpus pithecogallus</i> and Their Tyrosinase Inhibitory Activities

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