New perspectives on the face in fetal alcohol syndrome: What anthropometry tells us

Moore, Elizabeth S.; Ward, Richard E.; Jamison, Paul L.; Morris, Colleen A.; Bader, Patricia I.; Hall, Bryan D.

doi:10.1002/ajmg.10197

Cited by 56 publications

(68 citation statements)

References 76 publications

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“…Thomas and co-workers 41 have published norms for palpebral fissure length at 29 weeks gestation to 14 years. There are a number of opinions about which norms are appropriate, [41][42][43][44] but it is generally agreed that all are flawed in some respect.…”

Section: Commentsmentioning

confidence: 99%

Fetal alcohol spectrum disorder: Canadian guidelines for diagnosis

Chudley

Conry²,

Cook³

et al. 2005

Canadian Medical Association Journal

753

763

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THE DIAGNOSIS OF FETAL ALCOHOL SPECTRUM DISORDER (FASD) is complex and guidelines are warranted. A subcommittee of the Public Health Agency of Canada's National Advisory Committee on Fetal Alcohol Spectrum Disorder reviewed, analysed and integrated current approaches to diagnosis to reach agreement on a standard in Canada. The purpose of this paper is to review and clarify the use of current diagnostic systems and make recommendations on their application for diagnosis of FASD-related disabilities in people of all ages. The guidelines are based on widespread consultation of expert practitioners and partners in the field. The guidelines have been organized into 7 categories: screening and referral; the physical examination and differential diagnosis; the neurobehavioural assessment; and treatment and follow-up; maternal alcohol history in pregnancy; diagnostic criteria for fetal alcohol syndrome (FAS), partial FAS and alcohol-related neurodevelopmental disorder; and harmonization of Institute of Medicine and 4-Digit Diagnostic Code approaches. The diagnosis requires a comprehensive history and physical and neurobehavioural assessments; a multidisciplinary approach is necessary. These are the first Canadian guidelines for the diagnosis of FAS and its related disabilities, developed by broad-based consultation among experts in diagnosis

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Section: Commentsmentioning

confidence: 99%

Fetal alcohol spectrum disorder: Canadian guidelines for diagnosis

Chudley

Conry²,

Cook³

et al. 2005

Canadian Medical Association Journal

753

763

View full text Add to dashboard Cite

show abstract

“…Therefore, some investigators have sought to find subtle anomalies in alcohol-exposed individuals, using extended anthropometric protocols. Moore et al [54,55] investigated 21 craniofacial anthropometric measurements in 100 prenatally exposed individuals in an attempt find such subtle indicators of prenatal alcohol exposure. These investigators found that six anthropometric facial measurements discriminated alcohol-exposed individuals from controls [56].…”

Section: D Facial Photographymentioning

confidence: 99%

Identification of Children With Prenatal Alcohol Exposure

Coriale¹,

Fiorentino²,

Kodituwakku

et al. 2014

Curr Dev Disord Rep

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The term "fetal alcohol spectrum disorders" (FASD) denotes the broad spectrum of morphological changes and functional deficits seen in children exposed to alcohol prenatally. While some children on the spectrum show the characteristic pattern of malformations called "fetal alcohol syndrome" (FAS), a significant proportion of alcohol-exposed children do not evidence clinically identifiable morphological alterations. The term "alcohol-related neurodevelopmental disorder" (ARND) is used to label the latter group. The identification of children with ARND has proven to be challenging because of the lack of clinically discernable physical signs. Therefore, some investigators have used the strategy of assessing maternal drinking during pregnancy and then tracking developmental outcomes in offspring longitudinally. Other methods that investigators have utilized to identify children with prenatal alcohol exposure in population-based studies include multi-source surveillance and active case ascertainment. In the current review, we discuss the merits and demerits of these methodologies and then present novel methods of identifying prenatal alcohol exposure (e.g., biomarkers) and subtle effects of morphological alterations and neural effects (e.g., neuroimaging).

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“…The full range of possible outcomes resulting from maternal alcohol use during pregnancy are referred to as Fetal Alcohol Spectrum Disorders (FASD) (Barr and Streissguth, 2001). The most severe outcome is known as Fetal Alcohol Syndrome (FAS), and the less severe forms are commonly referred to as Partial FAS (Abel, 1998;Moore et al, 2002). The expression of full FAS is found in children whose mothers have a history of chronic heavy alcohol use or frequent heavy intermittent alcohol use in pregnancy.…”

Section: Prenatal Exposure To Alcoholmentioning

confidence: 99%

“…The expression of full FAS is found in children whose mothers have a history of chronic heavy alcohol use or frequent heavy intermittent alcohol use in pregnancy. The diagnosis of FAS is based on a set of criteria comprised of abnormalities in three main areas: characteristic physical abnormalities, growth retardation, and central nervous system abnormalities with intellectual impairment (Abel, 1998;Moore et al, 2002).…”

Section: Prenatal Exposure To Alcoholmentioning

confidence: 99%