New perspectives in the treatment of obstructive sleep apnea–hypopnea syndrome

Cortés-Reyes, Édgar; Parrado-Bermúdez, Katherine; Escobar-Córdoba, Franklin

doi:10.1016/j.rcae.2016.07.002

Cited by 3 publications

(3 citation statements)

References 89 publications

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“…CPAP therapy is indicated in all patients with an AHI greater than 15, independently from the presence of comorbidities, type of work and severity of symptoms; if the AHI is above 5 and below 15, CPAP is indicated in the presence of symptoms (i.e. sleepiness, impaired cognition, mood disorders) or in the presence of hypertension, coronary artery disease or previous cerebrovascular accidents [8,25,27]. Obstructive Sleep Apnea: A Pathophysiology and Pharmacotherapy Approach http://dx.doi.org/10.5772/intechopen.77981…”

Section: Continuous Positive Airway Pressure (Cpap)mentioning

confidence: 99%

“…Overnight application of these devices significantly reduces the AHI and few studies have shown similar efficacy compared with MAS. This type of implants could be used in patients with few teeth, exaggerated gag reflex, or intolerance for classic MADs [27]. Although its efficacy is still undetermined to recommend the use of these oral appliances in clinical practice [30].…”

Section: Oral Appliancesmentioning

confidence: 99%

“…Evidence has demonstrated, that bariatric surgery is co-adjuvant in the treatment of OSA, effectively reducing severity in up to 75% of cases. But, the remission rate for OSA 2 years after bariatric surgery in relation to the quantity of weight loss is up to 40% [27].…”

Section: Weight Control and Bariatric Surgerymentioning

confidence: 99%

See 2 more Smart Citations

Obstructive Sleep Apnea: A Pathophysiology and Pharmacotherapy Approach

Jyothi¹,

Prasad²,

Rajalakshmi³

et al. 2019

Noninvasive Ventilation in Medicine - Recent Updates

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Obstructive sleep apnea (OSA) is a common sleep disorder characterized by complete cessation of upper airflow during sleep, leading to repetitive episodes of desaturations and arousals. The symptoms include excessive daytime somnolence and are associated with a significant cardiovascular morbidity and mortality. The prevalence of OSA is higher in men with an approximate rate of 14 and 5% in women respectively. Typical risk factors for obstructive sleep apnea in the normal adult population are obesity, aging, gender, menopause, ethnicity, genetical predisposition, craniofacial anatomy, smoking, alcohol consumption and some other factors such as REM sleep, surface tension, and impaired sensory processing. Several screening questionnaires can be performed in outpatient settings to identify the patient symptoms. Polysomnography is considered as the gold standard for diagnosis of OSA. Different surgical treatments and devices are readily available for an effective management of this disease. Proper diagnosis and treatment improves not only the quality of life but also relatively decreases patient morbidity and mortality. A multifaceted approach is necessary for an accurate management of the OSA.

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Section: Continuous Positive Airway Pressure (Cpap)mentioning

confidence: 99%

Section: Oral Appliancesmentioning

confidence: 99%

See 1 more Smart Citation

Obstructive Sleep Apnea: A Pathophysiology and Pharmacotherapy Approach

Jyothi¹,

Prasad²,

Rajalakshmi³

et al. 2019

Noninvasive Ventilation in Medicine - Recent Updates

View full text Add to dashboard Cite

show abstract

Cost-utility and budget impact analysis of CPAP therapy compared to no treatment in the management of moderate to severe obstructive sleep apnea in Colombia from a third-party payer perspective

Robles¹,

Gil-Rojas²,

Amaya³

et al. 2023

Expert Review of Pharmacoeconomics & Outcomes Research

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Obstructive Sleep Apnea: New Concepts, Mechanism, and Therapy

2017

Indian Journal of Sleep Medicine

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Continuous positive airway pressure (CPAP) is the gold standard for the management of obstructive sleep apnea (OSA). However, studies have shown that only around half use the device at the minimum recommended level of ≥4 hours/night. The compliance further drops to 17% after 5 years. Thus, there is need to develop and apply new modalities for the OSA. Also, if the treatment of OSA is directed toward the mechanism, the results are likely to be better. This review is aimed at mechanismdirected treatment for OSA.

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New perspectives in the treatment of obstructive sleep apnea–hypopnea syndrome

Cited by 3 publications

References 89 publications

Obstructive Sleep Apnea: A Pathophysiology and Pharmacotherapy Approach

Obstructive Sleep Apnea: A Pathophysiology and Pharmacotherapy Approach

Cost-utility and budget impact analysis of CPAP therapy compared to no treatment in the management of moderate to severe obstructive sleep apnea in Colombia from a third-party payer perspective

Obstructive Sleep Apnea: New Concepts, Mechanism, and Therapy

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