New perspectives and insights to Asian systemic lupus erythematosus: renal disease, genetic predisposition and disease activity

A study of the influence of ethnicity on serology and clinical features in lupus

“…A negative association with renal involvement was observed in the European patients when compared with the other ethnic groups, a result consistent with previous reports (6,27,(31)(32)(33).…”

“…In a systematic review of SLE in Asia, higher rates of renal involvement were described in Asian patients (21-65% at diagnosis and 40-82% at follow-up) when compared with White patients (6,31). Renal disease was also more common in Black SLE patients in our study as has previously been reported (7,27,32).…”

Long‐term renal outcomes in multi‐ethnic Southeast Asians with lupus nephritis: a retrospective cohort study

“…Current understanding of long‐term clinical outcomes in LN is generally derived from studies of homogeneous Caucasian, Chinese, Korean or Japanese populations, with less known about prognosis in other ethnic groups and regions in Asia. Thus knowledge gaps persist in the diverse group of patients collectively labelled as ‘Asian lupus’ . We aimed to evaluate the long‐term renal outcome and identify risk factors for CKD in a multi‐ethnic Southeast Asian population with biopsy‐proven LN.…”

“…Thus knowledge gaps persist in the diverse group of patients collectively labelled as 'Asian lupus'. 15,16 We aimed to evaluate the long-term renal outcome and identify risk factors for CKD in a multi-ethnic Southeast Asian population with biopsy-proven LN.…”

Transplant outcomes in kidney recipients with lupus nephritis, and systematic review

“…Studies of Asian recipients with LN are scarce except in China, 11,12 although LN is common in Asians. 13 Furthermore, a pooled analysis involving heterogeneous recipients with LN is needed because the number of patients included in most previous studies was small or modest. The present study is the first to evaluate graft failure (GF), death-censored GF (DCGF), and patient survival in Korean kidney recipients with LN, and to conduct a pooled analysis of graft survival with previous studies.…”