New Parameter Derived from Three-Dimensional Speckle-Tracking Echocardiography for the Estimation of Left Ventricular Filling Pressure in Nondilated Hearts

Abstract

The novel parameter FRe/SRe has potential as a surrogate marker of LV filling pressure. Especially in nondilated hearts, FRe/C-SRe and FRe/A-SRe may be useful to more accurately predict LV filling pressure than E/e', although their applicability in dilated hearts requires further investigation.

Left ventricular end‐diastolic strain rate recovered in hypothyroidism following levothyroxine replacement therapy: A strain rate imaging study

“…Diastolic SR has been shown to be useful to detect subclinical myocardial diastolic dysfunction . Tiryakioglu et al reported impaired regional LV diastolic strain rate parameters, including SRe and SRa in hypothyroidic patients, consistent with our results in SRa.…”

“…Particularly, average E/e′ has been considered as the most reliable echocardiographic parameter to reflect LV filling pressure . However, the Doppler parameters have been shown to be less sensitive to detect alteration of diastolic performance . E/e′ is subject to angle‐dependence and is restricted in the presence of moderate to severe mitral pathologies, besides extrapolation of global diastolic function by regional measurements also seems problematic, especially in patients with regional wall motion abnormality …”

“…16,17 E/e′ is subject to angle-dependence and is restricted in the presence of moderate to severe mitral pathologies, besides extrapolation of global diastolic function by regional measurements also seems problematic, especially in patients with regional wall motion abnormality. 17 Diastolic SR has been shown to be useful to detect subclinical myocardial diastolic dysfunction. 8 Compliance is influenced by myocardial stiffness and extracellular matrix, which has been detected in hypothyroidism using CMR.…”

Left Ventricular Diastolic Function After Aortic Valve Replacement for Chronic Aortic Regurgitation

“…The strategy of integrating these two parameters has also been applied and justified in a large multicenter study by Anderson and associates [8] who reported an accuracy of 87% in identifying patients with elevated left ventricular filling pressure. Other novel parameters, such as the ratio of early ventricular filling, derived from the time derivative of left ventricular volume relative to the early diastolic strain rate measured by speckle-tracking echocardiography, might represent promising alternatives; however, their feasibility and reproducibility merit further scrutiny [6,15].…”

Novel Estimation of Left Ventricular Filling Pressure Using 3-D Speckle-Tracking Echocardiography: Assessment in a Decompensated Systolic Heart Failure Model

“…We previously determined that FRe/SRe could estimate filling pressure in dogs with non-dilated hearts that have preserved systolic function (Sakurai et al 2017). Although this experiment included two models of volume overload and myocardial ischemia, a significant correlation between FRe/SRe and filling pressure could not be identified in the myocardial ischemia model because of the small number of data sets.…”