New opportunities provided by modernized small-angle neutron scattering two-detector system instrument (YuMO)

Abstract

Main features of the modernized small-angle neutron scattering spectrometer (YuMO) at IBR-2M pulsed reactor are described. New installations for sample environment of the spectrometer are highlighted. The modernized SANS instrument (YuMO) is equipped with a new type of position sensitive detector as well as two detector system which provide a unique dynamic range (Q max /Q min ratio is about 90).Sample environment is extended with a magnetic system (magnetic field about 2.5 Tesla), automated high pressure setup which allows simultaneous SANS and volumetric high pressure studies and light illumination system. In particular, these developments led to considerable improvements of resolution of the instrument (about 1%) and opened the possibility to study anisotropic materials and perform efficient high pressure studies.

Fullerene Clustering in C70/N-Methyl-2-Pyrrolidone/Toluene Liquid System

“…Зразки (об'ємом 500 мкл) були за-литi у кварцевi кювети (Hellma Analytics) з товщи-ною 1 мм, якi знаходились при температурi 20 ∘ С. За фоновi зразки були використанi розчинники та їх сумiшi без фулерену, так званi, буфернi зразки. Для калiбрування iнтенсивностi розсiяння нейтро-нiв був використаний стандартний ванадiєвий зра-зок [30,31]. Обробка отриманих даних здiйснюва-лась програмою SAS у режимi згладжування [32].…”

The amyloidogenicity of the influenza virus PB1-derived peptide sheds light on its antiviral activity

“…Peptides used as a model for the influenza A virus polymerase complex PB1 subunit N-terminal region: MDVNPTLLFLKVPAQNAISTTFPYT (PB1 ) and TLLFLKVPAQNAISTTFPYT (PB1 (6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)). The peptides tested were: TLLFLKVP (PB1 (6)(7)(8)(9)(10)(11)(12)(13)); TLLFLKVPA (PB1(6-13)-Ala); and FITClabeled TLLFLKVPA (FITC-PB1(6-13)-Ala).…”

“…At the first stage, the interaction between the PB1(6-13) peptide fibrils and the PB1 subunit N-terminal region was studied by the SANS method ( Figure 5). (6)(7)(8)(9)(10)(11)(12)(13) in fibrillar form (black dots); and the normalized mathematical sum of the individual scattering curves for PB1 (6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25) and PB1(6-13) (red curve)…”

“…Analogous calculations were made in the study of the PB1(6-13) and PB1 (6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25) peptides' SAXS spectra in the q interval from 0.01 to 0.2 nm -1 . The changes in the singular decomposition zero and first components are shown in Figure 7(A) and 7(B), respectively.…”

Changes in the Area per Lipid Molecule by P–V–T and SANS Investigations

“…For the lipid systems investigations on small angle neutron scattering spectrometer YuMO [1,2] at IBR-2M reactor (Dubna, Russia) we created setup for simultaneously P-V-T and small angle neutron scattering (SANS) studies. [3] This setup allowed us to obtain the structural parameters of the samples, and the thermodynamic characteristics in the same time. Here we would like to present the calculation of value change of lipid membrane surface area based on our experiments.…”