New onset neuromyelitis optica in a young Nigerian woman with possible antiphospholipid syndrome: a case report

Komolafe, Morenikeji; Komolafe, E O; Sunmonu, Taofiki; Olateju, SO; Asaleye, Christianah Mopelola; Adesina, Olufemi Adeyinka; Badmus, SA

doi:10.1186/1752-1947-2-348

Cited by 20 publications

(12 citation statements)

References 10 publications

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“…Despite abundant evidence linking TS and MS, only few reports have suggested their association with NMO 8,[18][19][20] . Wingerchuk 8 reported a TS incidence rate of 35% in patients with NMO (17 of 48 patients) and more recently, Usmani 19 reported an incidence of 14% (8 of 57 patients).…”

Section: Discussionmentioning

confidence: 99%

Tonic spasms are a common clinical manifestation in patients with neuromyelitis optica

Abaroa¹,

Rodríguez-Quiroga²,

Melamud³

et al. 2013

Arq. Neuro-Psiquiatr.

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Tonic spasms have been most commonly associated with multiple sclerosis. To date, few reports of series of patients with neuromyelitis optica and tonic spasms have been published.Methods:We analyzed the characteristics and frequency of tonic spasms in 19 subjects with neuromyelitis optica. Data was collected using a semi-structured questionnaire for tonic spasms, by both retrospectively reviewing medical records and performing clinical assessment.Results:All patients except one developed this symptom. The main triggering factors were sudden movements and emotional factors. Spasms were commonly associated to sensory disturbances and worsened during the acute phases of the disease. Carbamazepine was most commonly used to treat the symptom and patients showed good response to the drug.Conclusions:Tonic spasms are a common clinical manifestation in patients with neuromyelitis optica.

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Section: Discussionmentioning

confidence: 99%

Tonic spasms are a common clinical manifestation in patients with neuromyelitis optica

Abaroa¹,

Rodríguez-Quiroga²,

Melamud³

et al. 2013

Arq. Neuro-Psiquiatr.

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“…The spasms lasted a few seconds to minutes with a frequency varying around 2 to 15 times a day, consistent with previous descriptions. [1][2][3][4][5][6][7] None of the patients experienced a preictal aura, loss of consciousness, loss of sphincter control, or postictal sequele.…”

Section: Commentmentioning

confidence: 99%

“…Wingerchuk et al 6 reported a toxic spasms incidence rate of 35% in patients with relapsing-remitting NMO(17 of 48 patients). Komolafe et al 5 subsequently described a 28- year-old Nigerian woman with NMO who presented with neck pain, paroxysmal tonic spasms, and spastic quadriplegia. The observations by Wingerchuk et al and our own finding that paroxysmal tonic spasms are more common in NMO suggest that NMO be included in the differential diagnosis of such patients.…”

Section: Commentmentioning

confidence: 99%

Association Between Paroxysmal Tonic Spasms and Neuromyelitis Optica

Usmani¹

2012

Arch Neurol

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“…Among the non‐organ‐specific autoimmune diseases are SLE, SS, antiphospholipid syndrome or sarcoidosis (class IV) [20,106–112]. Autoantibodies against nuclear antigens can be detected in NMO without clinical evidence of systemic autoimmune diseases.…”

mentioning

confidence: 99%

EFNS guidelines on diagnosis and management of neuromyelitis optica

Sellner

Boggild

Clanet

et al. 2010

Euro J of Neurology

405

353

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Background and purpose: Neuromyelitis optica (NMO) or Devic¢s disease is a rare inflammatory and demyelinating autoimmune disorder of the central nervous system (CNS) characterized by recurrent attacks of optic neuritis (ON) and longitudinally extensive transverse myelitis (LETM), which is distinct from multiple sclerosis (MS). The guidelines are designed to provide guidance for best clinical practice based on the current state of clinical and scientific knowledge. Search strategy: Evidence for this guideline was collected by searches for original articles, case reports and meta-analyses in the MEDLINE and Cochrane databases. In addition, clinical practice guidelines of professional neurological and rheumatological organizations were studied. In addition, guidance for the work-up and diagnosis of spatially limited NMO spectrum disorders is provided by the task force. Due to lack of studies fulfilling requirement for the highest levels of evidence, the task force suggests concepts for treatment of acute exacerbations and attack prevention based on expert opinion. Conclusions: Studies on diagnosis and management of NMO fulfilling requirements for the highest levels of evidence (class I-III rating) are limited, and diagnostic and therapeutic concepts based on expert opinion and consensus of the task force members were assembled for this guideline. ObjectivesTo provide guidelines for best practice diagnosis and management of adult neuromyelitis optica based on the current state of clinical and scientific knowledge.

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New onset neuromyelitis optica in a young Nigerian woman with possible antiphospholipid syndrome: a case report

Cited by 20 publications

References 10 publications

Tonic spasms are a common clinical manifestation in patients with neuromyelitis optica

Tonic spasms are a common clinical manifestation in patients with neuromyelitis optica

Association Between Paroxysmal Tonic Spasms and Neuromyelitis Optica

EFNS guidelines on diagnosis and management of neuromyelitis optica

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