New-onset Alice in Wonderland syndrome following brucellosis

Abstract

background. We report a rare association of Alice in Wonderland syndrome and brucellosis. Alice in Wonderland syndrome is a term applied to altered perceptions of the size or shape of own body or other objects. It can occur in a variety of disorders, including migraine, epilepsy, infections, and brain lesions. Brucellosis is a contagious zoonosis caused by infected milk or meat from animals, mainly goats. It causes a fever known as undulant or Malta fever, associated with gastrointestinal symptoms. case. A young 16 year-old male manifests Alice in Wonderland syndrome and migraine headache after suffering from brucellosis. Symptoms are represented by distortion of objects, animals, humans, which appear deformed, so called metamorphopsias. This is a strange case in which a somatosensory syndrome appears after suffering from an infectious disease. Conclusions. Mechanisms of this case are unclear, we hypothesize a toxic-infective cause, targeting brain parietal lobe. responsible for somesthesic functions.