The connection between neutrino physics, nucleosynthesis of elements in astrophysical sites, laboratory measurements with rare exotic nuclei and astronomical observations is discussed. The key role played by neutrinos is emphasized and the close connection between neutrino physics and nucleosynthesis is highlighted.Understanding where and how various nuclei are synthesized during the evolution of the Universe is one of the key questions of modern science. Element synthesis is thought to be a multi-site and multi-epoch process as depicted in Figure 1. Tackling the question of the origin of elements requires a multitude of tools: High-quality observations of stellar spectra, laboratory atomic physics data, modeling stellar photospheres as well as theoretical and experimental investigations of the relevant nuclear processes. In addition, typically copious amounts of neutrinos are present in most nucleosynthesis sites. This feature makes neutrino physics and neutrino-nucleus interactions salient components of many nucleosynthesis scenarios. This very close link between astronomical observations, neutrino physics, and nucleosynthesis is depicted in Figure 2 and was described in detail in a recent special issue of Journal of Physics G where the reader is referred to for a more complete explanation of many details [1].In nuclear physics on the theoretical side there have been significant accomplishments during the last decade in calculations with microscopic ab initio methods, driven in part by advances in computational capabilities. The most salient of these results is the realization of the necessity of incorporating three-body forces, in addition to the conventional two-body forces, to describe a wide range of nuclear phenomena. On the experimental side several facilities, already operating or under construction, with intense beams of rare isotopes now have the ability to explore nuclear physics far from stability, at the r-process nucleosynthesis path [2].There is considerable debate about the astrophysical site of the r-process nucleosynthesis, the two most favorite sites being core-collapse supernovae and neutron-star mergers. Neutrinos not only play a crucial role in the dynamics of these sites, but they also control the value of the electron fraction, the parameter determining the yields in the r-process. (For a recent brief summary see Ref. [3]). Understanding a core-collapse supernova requires answers to a variety of questions some of which need to be answered by nuclear physics, both theoretically and experimentally: Analysis of the formation and subsequent cooling of the neutron star involves high-density equation of state for nuclear matter. Studies of the oscillations of neutrinos as they travel from the neutrinosphere to where r-process or neutrino heating of the shock may take place need knowledge of neutrino properties. One should keep in mind that there are still many puzzles in neutrino physics. For example the near symmetry between second and third generations arXiv:1410.5866v1 [nucl-th]