New molecular targets in the treatment of rheumatoid arthritis
Beth I. Wallace,
Laura Cooney,
David A. Fox
Abstract:Purpose of review
This review will discuss selected emerging molecular targets and associated potential therapeutic agents for rheumatoid arthritis (RA)-directed treatment.
Recent findings
Agents in active development for RA treatment include those targeted to CD40 and CD40 ligand, programmed death protein 1 (PD-1), and granulocyte-macrophage colony-stimulating factor (GM-CSF). Several other molecules with a strong theoretical role in RA pathogenesis an… Show more
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