New methodology to assess activity status of occlusal caries in primary teeth using laser fluorescence device

Braga, Mariana Minatel; Benedetto, Monique Saveriano De; Imparato, José Carlos Pettorossi; Mendes, Fausto Medeiros

doi:10.1117/1.3463007

Cited by 33 publications

(39 citation statements)

References 24 publications

(38 reference statements)

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“…5 Another clinical study, using a different laser fluorescence device (LF: this consists of a 655-nm emitted diode laser) with occlusal caries, demonstrated that after air drying for 3 and 15 s, LF values of active caries, in which caries activity was determined by VE, presented higher than those of inactive caries. 29 There were also studies regarding the dehydration effect using OCT. For one study, dehydration was induced by the specimens in air at room temperature for 30 min. The results showed that hydration state affects the reflectivity of demineralized porous enamel, and the effect can be potentially used for assessment of early enamel lesion using OCT. 30 For another study, dehydration was produced in a controlled environment for 30 s. The air pressure was set to 15 psi, and the computer-controlled air nozzle was positioned 2 cm away from the sample.…”

Section: Discussionmentioning

confidence: 99%

Pilot clinical study to assess caries lesion activity using quantitative light-induced fluorescence during dehydration

et al. 2017

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"Pilot clinical study to assess caries lesion activity using quantitative light-induced fluorescence during dehydration," J. Biomed. Opt. Abstract. This study aimed to evaluate the ability of quantitative light-induced fluorescence (QLF) to assess caries lesion activity using visual examination (VE) as the gold standard. Twenty-four visible white spot lesions on buccal surfaces were examined from 23 children, ages 9 to 14 years. At baseline, the surface was hydrated with water, and thereafter, it was dehydrated with continuous compressed air during image acquisition. QLF images were acquired at 0 (baseline), 5, and 15 s. QLF variables [QLF V : fluorescence loss (ΔF), lesion size (S), ΔQ: ΔF × S] was recorded. Changes-in-QLF V per second (ΔQLF V ) were determined: ΔQLF V ¼ ðQLF VN − QLF VBaseline Þ∕N, where N indicates dehydration time. One experienced dentist conducted VE independently using a dental unit's light, compressed air, and explorer. QLF V and ΔQLF V of the active group (n ¼ 11) were compared with those of the inactive group (n ¼ 13) using two-sample t -tests. As the surface was dehydrated, S and ΔQ values of the active group increased, whereas QLF V of the inactive group showed only a small change. ΔQLF V of the active group were larger than those of the inactive group; however, the difference did not reach statistical significance (p > 0.11). Within the limitations of this study, QLF data indicated increments for lesions designated as active and minimal change for lesions defined as inactive.

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Section: Discussionmentioning

confidence: 99%

Pilot clinical study to assess caries lesion activity using quantitative light-induced fluorescence during dehydration

et al. 2017

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“…In our previous work, the seven ICDAS classes were dichotomized into two classes, which resulted in 80.8% accuracy for automatic detection of two classes across 72 images [20]. Other studies also recategorized ICDAS scores to fewer categories than the initial 7 scores [7,21,[13][14][19][20]. A heuristic super classifier method is applied to select only high ranking features thereby reducing the feature space for the development of the classifier model [22].…”

Section: Feature Selection and Classificationmentioning

confidence: 99%

An automated dental caries detection and scoring system for optical images of tooth occlusal surface

Ghaedi

Gottlieb

Sarrett

et al. 2014

2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society

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Dental caries are one of the most prevalent chronic diseases. The management of dental caries demands detection of carious lesions at early stages. This study aims to design an automated system to detect and score caries lesions based on optical images of the occlusal tooth surface according to the International Caries Detection and Assessment System (ICDAS) guidelines. The system detects the tooth boundaries and irregular regions, and extracts 77 features from each image. These features include statistical measures of color space, grayscale image, as well as Wavelet Transform and Fourier Transform based features. Used in this study were 88 occlusal surface photographs of extracted teeth examined and scored by ICDAS experts. Seven ICDAS codes which show the different stages in caries development were collapsed into three classes: score 0, scores 1 and 2, and scores 3 to 6. The system shows accuracy of 86.3%, specificity of 91.7%, and sensitivity of 83.0% in ten-fold cross validation in classification of the tooth images. While the system needs further improvement and validation using larger datasets, it presents promising potential for clinical diagnostics with high accuracy and minimal cost. This is a notable advantage over existing systems requiring expensive imaging and external hardware.

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“…For the assessment of caries activity, a methyl red solution at a concentration of 0.1% was applied on each section [MacGregor, 1961;Ekstrand et al, 1998b;Braga et al, 2010aBraga et al, , 2010b. This indicator is capable of indicating a defined color change at different pH values (approx.…”

Section: Histological Preparation and Examinationmentioning

confidence: 99%

Diagnostic Accuracy of a Bioluminescence System for the Assessment of Caries Activity on Occlusal Surfaces

et al. 2018

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Objective: Assessment of caries lesion activity is usually performed using visual-tactile criteria. A new approach is to use a system consisting of a photoprotein, which is specific for free calcium ions, along with an integrated camera that visualizes the elevated calcium ions on the lesion as a light signal (bioluminescence). This study aimed to evaluate the reproducibility and diagnostic accuracy of a newly developed bioluminescence system to assess caries lesion activity on occlusal surfaces in vitro. Materials and Methods: Ninety-four extracted permanent teeth with sound surfaces and both active and inactive caries lesions were included. The extent and activity of the investigation sites were classified visually according to the International Caries Detection and Assessment System. Digital images of the teeth were produced by the bioluminescence system and the images were analyzed for the presence of caries activity (the bioluminescent areas at the investigation sites). The images were reanalyzed after 4 weeks. Teeth were hemisected and methyl red dye was applied on the sections to validate lesion activity histologically. Results: Agreement between the bioluminescence readings was shown by κ values of 0.802–0.917. A significant positive correlation (p < 0.001) was found across all methods (r_s 0.618–0.811). Sensitivity and specificity for activity assessment using histology as the gold standard (cut-off: active/inactive) were, respectively, 83.6 and 85.0% for the visual assessment, and 92.5 and 90.0% for the bioluminescence method. Comparison of areas under the receiver-operating characteristic curves showed no significant difference between the visual and bioluminescence systems (p = 0.094). Conclusion: The bioluminescence system demonstrated high in vitro reproducibility and good diagnostic accuracy for activity assessment of caries lesions on occlusal surfaces which were not significantly different from the values obtained in the visual assessment.

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New methodology to assess activity status of occlusal caries in primary teeth using laser fluorescence device

Cited by 33 publications

References 24 publications

Pilot clinical study to assess caries lesion activity using quantitative light-induced fluorescence during dehydration

Pilot clinical study to assess caries lesion activity using quantitative light-induced fluorescence during dehydration

An automated dental caries detection and scoring system for optical images of tooth occlusal surface

Diagnostic Accuracy of a Bioluminescence System for the Assessment of Caries Activity on Occlusal Surfaces

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