New magnetic nanoparticles for biotechnology

Hütten, Andreas; Sudfeld, D.; Ennen, Inga; Reiss, Günter; Hachmann, Wiebke; Heinzmann, Ulrich; Wojczykowski, Klaus; Jutzi, Peter; Saikaly, W.; Thomas, G.

doi:10.1016/j.jbiotec.2004.04.019

Cited by 151 publications

(98 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As samples. Also, the maximum of the sensitivity is at very low fields of only 8 Oe, making it the system of choice for the detection of small or weak magnetic objects 166 , for example microscopic magnetic particles as they are used in biotechnology and medical applications 191,192 . A unique feature that can be added by soft magnetoresistive sensors in this respect will be introduced in the next paragraph.…”

Section: Demonstrator: Magnetic Detection On a Curved Surfacementioning

confidence: 99%

“…Magnetic particles are widely used for diagnostic or therapeutic purposes in biology and medicine [190][191][192]194 , implying the necessity of implementation of magnetic field sensors in complex biomedical systems. In this respect, magnetoresistive sensors, especially those relying on the GMR effect represent an efficient solution for the use in fluidic biodetection platforms due to their high sensitivity 195 .…”

Section: Gmr Sensors In Circumferential Geometrymentioning

confidence: 99%

See 1 more Smart Citation

Stretchable Magnetoelectronics

et al. 2011

View full text Add to dashboard Cite

Abstract:In this work, stretchable magnetic sensorics is successfully established by combining metallic thin films revealing a giant magnetoresistance effect with elastomeric materials. Stretchability of the magnetic nanomembranes is achieved by specific morphologic features (e.g. wrinkles), which accommodate the applied tensile deformation while maintaining the electrical and magnetic integrity of the sensor device. The entire development, from the demonstration of the world-wide first elastically stretchable magnetic sensor to the realization of a technology platform for robust, ready-touse elastic magnetoelectronics with fully strain invariant properties, is described. The prepared soft giant magnetoresistive devices exhibit the same sensing performance as on conventional rigid supports, but can be stretched uniaxially or biaxially reaching strains of up to 270% and endure over 1,000 stretching cycles without fatigue. The comprehensive magnetoelectrical characterization upon tensile deformation is correlated with in-depth structural investigations of the sensor morphology transitions during stretching.With their unique mechanical properties, the elastic magnetoresistive sensor elements readily conform to ubiquitous objects of arbitrary shapes including the human skin. This feature leads electronic skin systems beyond imitating the characteristics of its natural archetype and extends their cognition to static and dynamic magnetic fields that by no means can be perceived by human beings naturally.Various application fields of stretchable magnetoelectronics are proposed and realized throughout this work. The developed sensor platform can equip soft electronic systems with navigation, orientation, motion tracking and touchless control capabilities. A variety of novel technologies, like smart textiles, soft robotics and actuators, active medical implants and soft consumer electronics will benefit from these new magnetic functionalities. Michael Melzer: Stretchable MagnetoelectronicsOutline 4

show abstract

Section: Demonstrator: Magnetic Detection On a Curved Surfacementioning

confidence: 99%

Section: Gmr Sensors In Circumferential Geometrymentioning

confidence: 99%

Stretchable Magnetoelectronics

et al. 2011

View full text Add to dashboard Cite

show abstract

“…Certamente, esses materiais podem ser revestidos com moléculas biológicas para fazer com que os mesmos interajam com outras espécies biológicas e, desse modo, fornecendo um meio controlável de endereça-mento dessas espécies no organismo [5]. Além disso, os materiais nanoestruturados são magnéticos, o que significa que os mesmos seguem as leis de Coulomb e podem, portanto, serem manipulados por um campo magnético externo [6][7].…”

Section: Introductionunclassified

“…Isto porque esses materiais apresentam tamanho na extensão de alguns a dezenas de nanômetros, os quais são menores ou comparáveis ao tamanho de uma célula (10 -100 µm), de um vírus (20 -450 nm), de uma proteína (5 -50 nm) ou de um gene (2 nm de largura e 10 -100 nm de comprimento) [3][4]. Isto significa que as nanopartículas podem ser empregadas como uma entidade biológica.Certamente, esses materiais podem ser revestidos com moléculas biológicas para fazer com que os mesmos interajam com outras espécies biológicas e, desse modo, fornecendo um meio controlável de endereça-mento dessas espécies no organismo [5]. Além disso, os materiais nanoestruturados são magnéticos, o que significa que os mesmos seguem as leis de Coulomb e podem, portanto, serem manipulados por um campo magnético externo [6][7].…”

unclassified

Nanopartículas magnéticas: o cobalto

Sargentelli

Ferreira

2010

Eclet. Quim.

View full text Add to dashboard Cite

The development of nanoparticles has been intensively pursued because of their technological importance. The magnetic nanoparticulate materials exhibit a series of interesting properties between which are mentioned the electrical, optical, magnetic and chemical properties. Magnetic nanostructures can be used in microelectronic and in medicine as in: magnetic memory storage, magnetic transport of biochemical complexes, magnetic resonance imaging, among others. The magnetic properties of nanoparticles there are very sensitive to its size and form. In this direction, many efforts they have been carried through with the intention of to control the form and distribution of the size of the nanoparticles. In the last few decades nanoparticles constituted by iron oxides had been studied. However, more recently, the focus of the researches has come back to others transitions metals. Amongst these, the cobalt comes being investigated due to its high magnetic susceptibility. In this context, the present article has the aim of to presents and to effect a comparative analysis of the more significant synthetic ways utilized in the present moment to obtain cobalt nanoparticles.

show abstract

“…[5][6][7][8]. Some authors have even proposed the preparation of multifunctional nanoparticles or nanoplatforms with three or more functions (multi-gene vector, drug carrier, and heating properties for hyperthermia) [9,10].…”

mentioning

confidence: 99%

Antisense Oligonucleotides and Magnetic Nanoparticles for Targeted Diagnostic and Cancer Treatment

López-Díaz¹,

Mercado-Sáenz²,

Portero³

et al. 2017

MOJBM

View full text Add to dashboard Cite

The resistance of tumors to therapeutic intervention is a major problem in the efficacy of treatments. A recent strategy to overcome this problem proposes the association of antitumor drugs with colloidal nanoparticles. Here a hypothesis is suggested concerning the potential use of antisense Oligo Deoxy Nucleotide (ODN) labeled with iron nanoparticles for tumor antisense gene detection with magnetic resonance gene imaging and cancer treatment.Keywords: Antisense therapy; Magnetic field; Drug delivery; Nanoplatform IntroductionThe resistance of tumors to therapeutic intervention is a major problem in the efficacy of treatments. A recent strategy to overcome this problem proposes the association of antitumor drugs with colloidal nanoparticles, with the aim to avoid non- ConclusionThe applications of nanoparticles in biomedicine (nanobiotechnology) are increasing over time, being nowadays a promising area in research and health care, with future innovative methods for diagnostic and treatment of cancer.

show abstract

New magnetic nanoparticles for biotechnology

Cited by 151 publications

References 17 publications

Stretchable Magnetoelectronics

Stretchable Magnetoelectronics

Nanopartículas magnéticas: o cobalto

Antisense Oligonucleotides and Magnetic Nanoparticles for Targeted Diagnostic and Cancer Treatment

Contact Info

Product

Resources

About