New insights on bioactivities and biosynthesis of flavonoid glycosides

Yang, Bao; Liu, Huiling; Yang, Jiali; Gupta, Vijai Kumar; Jiang, Yueming

doi:10.1016/j.tifs.2018.07.006

Cited by 181 publications

(124 citation statements)

References 68 publications

Supporting

Mentioning

107

Contrasting

Order By: Relevance

“…Entomopathogenic fungi can perform biotransformation, leading to the generation of derivatives with higher activity. These processes are favorable, because they improve the absorbability of products (Yang et al 2018;Dou et al 2019;Kozłowska et al 2019).…”

Section: Nanoparticle Biosynthesis By Entomopathogenic Fungimentioning

confidence: 99%

“…Flavonoids are derivatives of plant polyphenols. These are glycosides with O-and C-glycosidic bonds connecting the base with sugar residues (Dymarska et al 2018a, b;Dou et al 2019), including most often glucose, rhamnose, galactose, xylose, and arabinose (Yang et al 2018). It is believed that the sugar group of flavonoids is the main factor affecting the absorption of these compounds by the human body (Sordon et al 2017).…”

Section: Flavonoid Biotransformationmentioning

confidence: 99%

“…In addition, flavonoids have anti-tumor and immunomodulatory activity and protective effects on the human nervous system. The consumption of foods containing flavonoids can prevent the development of heart disease, diabetes, and depression (Dymarska et al 2018a;Yang et al 2018;Dou et al 2019). They occur naturally in vegetables, fruits, cereals, wine, and tea (Yang et al 2018;Dou et al 2019).…”

Section: Flavonoid Biotransformationmentioning

confidence: 99%

See 2 more Smart Citations

Entomopathogenic fungi: unconventional applications

Litwin

Nowak

Różalska

2020

Rev Environ Sci Biotechnol

161

View full text Add to dashboard Cite

Entomopathogenic fungi (EPF) are microorganisms that cause fatal diseases of arthropods. The infection process involves several stages that consist of direct contact of the fungus with the surface of the cuticle of the attacked insect. The factors that determine the effectiveness of the infection process include lytic enzymes, secondary metabolites, and adhesins produced by EPF. Because of their high insecticidal effectiveness, these fungi are commonly used as biopesticides in organic farming. As the environment and farmlands are contaminated with many compounds of anthropogenic origin (e.g., pesticides), the effects of these toxic compounds on EPF and the mechanisms that affect their survival in such a toxic environment have been studied in recent years. This review presents information on the capacity of EPF to remove toxic contaminants, including alkylphenols, organotin compounds, synthetic estrogens, pesticides and hydrocarbons. Moreover, these fungi produce numerous secondary metabolites that can be potentially used in medicine or as antimicrobial agents. Despite their huge potential in biocontrol processes, the use of EPF has been underestimated due to a lack of knowledge on their abilities. In our work, we have presented the available data on the possibilities of the additional and unconventional use of these microorganisms.

show abstract

Section: Nanoparticle Biosynthesis By Entomopathogenic Fungimentioning

confidence: 99%

Section: Flavonoid Biotransformationmentioning

confidence: 99%

Section: Flavonoid Biotransformationmentioning

confidence: 99%

See 1 more Smart Citation

Entomopathogenic fungi: unconventional applications

Litwin

Nowak

Różalska

2020

Rev Environ Sci Biotechnol

161

View full text Add to dashboard Cite

show abstract

“…Flavonoids are composed of a group of diverse polyphenols with similar backbone structures (Xiao, 2017), and they have been shown to possess a wide range of biological activities, such as with anti-oxidant, antibacterial, immunomodulatory, anticancer, anti-inflammatory, and antithrombotic benefits (Xiao, 2017;Yang, Liu, Yang, Gupta, & Jiang, 2018). Traditionally, flavonoids can be categorized into six subclasses, including flavonols, flavones, isoflavonoids, flavanols, flavanones, and anthocyanins (Yang et al, 2018). By far, most of the flavonoids have been reportedly found in fruits, vegetables, and grains (Merken & Beecher, 2000).…”

Section: Minor Componentsmentioning

confidence: 99%

Antarctic Krill (Euphausia superba) Oil: A Comprehensive Review of Chemical Composition, Extraction Technologies, Health Benefits, and Current Applications

Xie

Gong

Wei

et al. 2019

Comp Rev Food Sci Food Safe

134

View full text Add to dashboard Cite

Antarctic krill (Euphausia superba) oil has been receiving increasing attention due to its nutritional and functional potentials. However, its application as a novel food ingredient has not yet been fully explored. This review summarizes the chemical composition, extraction technologies, potential health benefits, and current applications of krill oil, with the aim of providing suggestions for its exploitation. Krill oil is a unique lipid consisting of diverse lipid classes and is characterized by a high concentration (39.29% to 80.69%) of phospholipids (PLs) associated with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). It also contains considerable amounts of bioactive minor components such as astaxanthin, sterols, tocopherols, vitamin A, flavonoids, and minerals. The current technologies used in krill oil production are solvent extraction, nonsolvent extraction, super/subcritical fluid extraction, and enzyme‐assisted pretreatment extraction, which all greatly influence the yield and quality of the end‐product. In addition, krill oil has been documented to have various health benefits, including anti‐inflammatory effects, cardiovascular disease (CVD) prevention, women's health, neuroprotection, and anticancer activities. Although krill oil products used for dietary supplements have been commercially available, few studies have attempted to explore the underlying molecular mechanisms to elucidate how exactly the krill oil exerts different biological activities. Further studies should focus on this to improve the development of krill oil products for human consumption.

show abstract

“…However, the cellular uptake of bioactive compounds greatly contributes to their health benefits in vivo . FG, but not their corresponding aglycones, are transported by Na‐dependent glucose transporter 1 located in the membrane of various endothelial cells such as enterocytes and vascular endothelial cells (Yang, Liu, Yang, Gupta, & Jiang, ). Therefore, it can be speculated that the two kaempferol glycosides identified from C. oleifera meal in the present study may possess excellent in vivo bioactivity.…”

Section: Resultsmentioning

confidence: 99%

Two Kaempferol Glycosides Separated from Camellia Oleifera Meal by High‐Speed Countercurrent Chromatography and Their Possible Application for Antioxidation

Zheng

Chen

et al. 2019

Journal of Food Science

View full text Add to dashboard Cite

Recently, kaempferol and its glycosides have attracted considerable attention owing to their potentially health‐benefitting properties including protection against chronic diseases. Here, a microwave‐assisted extraction (MAE) method was developed for the extraction of total flavonoid glycosides (FG) from Camellia oleifera meal, a major agrifood waste largely generated as a byproduct from the Camellia oil processing industry. Compared with traditional extraction methods, MAE enables more efficient extraction of FG. High‐speed countercurrent chromatography was then applied to separate FG from MAE extract, and two major compounds were successfully separated with purities above 90.0% as determined by HPLC. These two compounds were further identified by UV, FT‐IR, ESI‐MS, 1H‐NMR, and 13C‐NMR as kaempferol 3‐O‐[α‐L‐rhamnopyranosyl‐(1→6)‐β‐D‐glucopyranosyl]‐7‐O‐β‐D‐glucopyranoside and kaempferol 3‐O‐[β‐D‐glucopyranosyl‐(1→4)‐α‐L‐rhamnopyranosyl]‐7‐O‐α‐L‐rhamnopyranoside, which were for the first time separated from C. oleifera meal. The results of antioxidant activity assay demonstrated that both compounds had excellent scavenging activity for DPPH radical, and exhibited protective effects against H2O2‐induced oxidative damage of vascular endothelial cells. The findings of this work suggest the possibility of employing C. oleifera meal as an attractive source of health‐promoting compounds, and at the same time facilitate its high‐value reuse and reduction of environmental burden.

show abstract

New insights on bioactivities and biosynthesis of flavonoid glycosides

Cited by 181 publications

References 68 publications

Entomopathogenic fungi: unconventional applications

Entomopathogenic fungi: unconventional applications

Antarctic Krill (Euphausia superba) Oil: A Comprehensive Review of Chemical Composition, Extraction Technologies, Health Benefits, and Current Applications

Two Kaempferol Glycosides Separated from Camellia Oleifera Meal by High‐Speed Countercurrent Chromatography and Their Possible Application for Antioxidation

Contact Info

Product

Resources

About