New insights into the role of chitosan oligosaccharide in enhancing growth performance, antioxidant capacity, immunity and intestinal development of weaned pigs

Abstract

Chitosan oligosaccharide (COS), an oligomer ofd-glucosamine, is a vital growth stimulant in the pig industry.

Effects of chitosan as growth promoter on diarrhea, nutrient apparent digestibility, fecal microbiota and immune response in weaned piglets

“…The present study showed a reduction of E.coli, Salmonella and Staphylococcus aureus populations in feces of piglets fed with CS. Likewise, previous study showed a lower population of E. coli in the caecum and colon of pigs fed diets with CS (Wan et al 2017). These results suggested that CS could inhibit the proliferation of intestinal pathogens.…”

“…Compared with other natural polysaccharides, a plethora of applications of this biopolymer has been found due to its high biocompatible, biodegradable and low toxicity nature (Jayakumar et al 2010;Dash et al 2011). Chitosan has been reported to modify the gastrointestinal physiology of pigs, influence the intestinal mucosal morphology and endocrine system during weaning (Xu et al 2013;Xu et al 2014;Wan et al 2017). In addition, CS has antibacterial potential in vivo (Han et al 2007;Wan et al 2017) and in vitro (Tsai and Hwang 2004).…”

“…Chitosan has been reported to modify the gastrointestinal physiology of pigs, influence the intestinal mucosal morphology and endocrine system during weaning (Xu et al 2013;Xu et al 2014;Wan et al 2017). In addition, CS has antibacterial potential in vivo (Han et al 2007;Wan et al 2017) and in vitro (Tsai and Hwang 2004). Overall, CS may offer a dietary means to modulate gut morphology and intestinal microbiota, thereby promote the productivity of farm animals.…”

Effects of dietary lysozyme levels on growth performance, intestinal morphology, immunity response and microbiota community of growing pigs

“…Therefore, the use of antibiotics like colistin sulfate as a growth promoter has been restricted or prohibited in China. The identification of effective antibiotic alternatives has been the focus of recent studies …”

“…The identification of effective antibiotic alternatives has been the focus of recent studies. [3][4][5] It is well known that lysozyme, 1,4--N-acetylmuramidase, specifically catalyses the hydrolysis of bacterial cell wall by cleavage of -1,4 linkages between N-acetylmuramic acid and N-acetylglucosamine of peptidoglycan. 6 It is secreted by polymorphonuclear leukocytes and found in tissue and bodily fluids, including egg white, tears and milk.…”