New insights into the qualitative phenolic profile of Ficus carica L. fruits and leaves from Tunisia using ultra-high-performance liquid chromatography coupled to quadrupole-time-of-flight mass spectrometry and their antioxidant activity

Abstract

RP-UHPLC-DAD-QTOF-MS gives new insights into the fig phenolic constituents that correlate with their antioxidant potency.

RP‐HPLC‐DAD‐ESI‐QTOF‐MS based metabolic profiling of the potential Olea europaea by‐product “wood” and its comparison with leaf counterpart

“…The first compounds that appeared were sugars and organic acids and last ones were secoiridoids and lignans (Table ). Furthermore, UV–vis detection data were used to primarily characterise the chemical structures, which showed equivalent to results in accordance with previous studies (Talhaoui et al, ; Klen et al, ; Mekky et al, ; Salido et al, ; Ammar et al, , ). Mass accurate determinations in the negative ionisation mode helped to identify the molecular formula of each molecular ion.…”

Antifungal, antibacterial and anticancer activities of Ficus drupacea L. stem bark extract and biologically active isolated compounds

“…Important biologically active molecules/compounds have been found in different organs of different Ficus species; e.g., sterols and triterpenes have been found in the root bark of Ficus chlamydocarpa, the stem bark of Ficus cordata (Kuete et al, 2008) and F. glomerata (Rahman et al, 1994), and in the leaf extracts of several Egyptian endemic Ficus species (Awad et al, 2012). Also, Oliveira et al (2010) found seven phytosterols, 18 fatty acids and 13 amino acids in the latex of Ficus carica, and recently Ammar et al (2015) found 18 phenolic compounds in the fruits. The biological activities of several compounds have been explored, including the activities of laburnetin and luteolin in F. chlamydocarpa and F. cordata against fungi and bacteria (Kuete et al, 2008), the antioxidant property of triterpenes and steroids in F. mysorensis (Awad et al, 2012) and the inhibitive activity of 6-O-acyl-â-D-glucosyl-â-sitosterols in F. carica against the proliferation of various cancer cells (Rubnov et al, 2001).…”

The UPLC–ESI–QqQLIT–MS/MS method for quantitative determination of phytochemicals in ethanolic extracts of different parts of eight Ficus species: Development and validation

“…The UPLC-ESI-QqQ LIT -MS/MS method in the MRM mode is rapid, sensitive, precise, efficient, and reproducible as compared to HPLC and LC-MS methods reported earlier. [3,6,8,9,[19][20][21][22][23] According to Yin-Xian et al, [7] the antioxidant property of crude extracts of Ficus species is due to the total phenolic and flavonoid contents. Therefore, F. benjamina fruits and leaves, which are edible, can be highly valuable for health due to the high total content of phenolics and flavonoids.…”

“…[3,6,8,9,[19][20][21][22][23] Similarly, quantitation of the bioactive compounds in F. carica, F. bhengalensis, F. religiosa, and F. deltoidea has been reported by HPLC or HPTLC. [9,[24][25][26][27][28] Catechin, epicatechin, rutin, and ferulic acid were quantified in the fruits of F. carica by HPLC. [11,20] Principal component analysis (PCA) is one of the most widely used multivariate techniques useful in dealing with large datasets for discrimination.…”