New information triggers prospective codes to adapt for flexible navigation
Stephanie M. Prince,
Teema A. Yassine,
Navya Katragadda
et al.
Abstract:Navigating a dynamic world requires rapidly updating choices by integrating past experiences with new information. In hippocampus and prefrontal cortex, neural activity representing future goals is theorized to support planning. However, it remains unknown how prospective goal representations incorporate new, pivotal information. Accordingly, we designed a novel task that precisely introduces new information using virtual reality, and we recorded neural activity as mice flexibly adapted their planned destinati… Show more
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