New indices of arterial stiffness correlate with disease severity and mid-term prognosis in acute decompensated heart failure

Zhou, Jiao; Wang, Yushu; Feng, Yongzeng; Chen, Xiaojing; Zhang, Qing

doi:10.1007/s11739-020-02486-x

Cited by 3 publications

(4 citation statements)

References 36 publications

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“…Our previous study reported that the AVI has a predictive value for the risk of composite events of MACE and hospitalization due to HF in cardiology outpatients [19]. Another study reported that the AVI was a strong predictor of the composite of all-cause death and rehospitalization for HF in patients admitted for acute HF [20]. Similar to existing vascular indices, such as PWV and CIMT, the AVI can be a predictive index of CV events.…”

Section: Discussionmentioning

confidence: 92%

“…However, few studies have examined the relationship between these measures and the occurrence of CV events [19,20]. In the present retrospective cohort study, we aimed to investigate the relationship between the arterial stiffness indices (AVI and API) and the occurrence of CV events in patients with apparent or subclinical atherosclerosis in Japan.…”

Section: Introductionmentioning

confidence: 98%

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A Noninvasive Arterial Stiffness Index to Estimate the Severity of Coronary Atherosclerosis in Patients Undergoing Coronary Angiography

Uchida,

Chen,

Minegishi

et al. 2024

JVD

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The early diagnosis and appropriate treatment of subclinical atherosclerosis before the onset of life-threatening cardiovascular (CV) diseases are major unmet medical needs in current clinical practice. Noninvasive arterial stiffness indices, the arterial velocity–pulse index (AVI) and the arterial pressure–volume index (API) have been associated with CV risks, conventional arterial stiffness indices, and the severity of coronary atherosclerosis. However, few studies have examined the relationship between these indices and the occurrence of CV events. We measured the AVI and API in 113 consecutive patients admitted to Yokohama City University Hospital for cardiac catheterization between June 2015 and March 2016. Patients were followed until September 2022, and the occurrence of CV events was assessed. The mean age was 71.2 ± 10.7 years, and 83 patients (73.5%) were male. In total, 80 patients (70.8%) had hypertension, 87 (77.0%) had dyslipidemia, and 91 (80.5%) had a history of ischemic heart disease (IHD). The mean follow-up duration was 1752 ± 819 days. Patients who received elective percutaneous coronary intervention (PCI) based on the results of coronary angiography (CAG) at the time of enrollment had significantly higher API than those who did not (38.5 ± 12.6, n = 17 vs. 31.3 ± 7.4, n = 96, p = 0.001). The API was independently associated with the risk of elective PCI in multiple logistic regression analysis. In conclusion, the API could be a useful indicator for estimating the need for coronary interventional treatment in patients with a high CV risk.

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Section: Discussionmentioning

confidence: 92%

Section: Introductionmentioning

confidence: 98%

A Noninvasive Arterial Stiffness Index to Estimate the Severity of Coronary Atherosclerosis in Patients Undergoing Coronary Angiography

Uchida,

Chen,

Minegishi

et al. 2024

JVD

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“…The study revealed that AVI and API can serve as indicators of illness severity and mid-term prognosis in hospitalized patients. Among patients with acute heart failure, those with an AVI ≥ 26 at discharge had a 2.75-fold higher rate of all-cause death or heart failure recurrence compared to patients with an AVI < 26 (95%CI: 1.411 to 5.349) [54]. Additionally, patients with diastolic heart failure exhibited an elevated AVI, translating to a 3.12-fold higher risk of cardiovascular events in comparison to patients with normal diastolic function [55].…”

Section: Heart Failurementioning

confidence: 97%

Arterial Stiffness and Cardiovascular Risk: The Role of Brachial Cuff-measured Index

Lin,

Xinyi,

Mengjiao

et al. 2023

Advanced Ultrasound in Diagnosis and Therapy

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Early detection of vascular disease is fundamental to the prevention and treatment of systemic vascular lesions. The timely identification of vascular damage can be achieved by comprehensively assessing the structural anomaly and/or functional degeneration of the vasculature. The assessment may to some extent indicate the long-term detrimental effects of cardiovascular disease (CVD) risk factors on vascular health. A key aspect in the evaluation of vascular function is the measurement of arterial stiffness. In 2012, the arterial velocity-pulse index (AVI) and arterial pressure-volume index (API) were introduced, which are noninvasively measured with a brachial cuff, and can reflect the status of arterial stiffness in both the aorta and the brachial artery.A large number of relevant studies have demonstrated the strong associations between AVI/API and various CVD risk factors, underlining the substantial relevance of the indices in CVD risk assessment. In this review, we provide a systematic review of the progresses made in brachial cuff-based measurements of arterial stiffness. In addition, we summarize the results of the recent studies focused on exploring the associations of AVI/API with relevant risk factors as well as their roles in CVD assessment.

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“…Other studies have also reported that the increase in arterial stiffness in chronic kidney disease (CKD) patients is an essential factor determining patients' cardiovascular prognosis [43,44]. The measures of arterial stiffness are also practical in predicting clinical outcomes in patients with heart failure [45,46]. In meta-analyses, both aortic PWV and baPWV are predictors of future cardiovascular events in various patient populations: every 1 SD increase in the aortic PWV and baPWV were associated with 47% and 19% increase respectively, in the risk of CVD [18,19].…”

Section: Prognostic Value Of the Measures Of Arterial Stiffnessmentioning

confidence: 99%

Incremental value of the measures of arterial stiffness in cardiovascular risk assessment

Lee¹,

Kim²

2022

Rev. Cardiovasc. Med.

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Predicting the occurrence of organ damage and future cardiovascular events is critical to improving patient prognosis through early personalized treatment. Although many tools have been developed and used for individuals' cardiovascular risk, they have limitations and unmet needs for improved risk stratification. For this purpose, arterial stiffness information can be practical. Arterial walls stiffen with age or prolonged exposure to various noxious stimuli such as high blood pressure, hyperglycemia, inflammation and oxidative stress. Differently from several methods of measuring arterial stiffness, pulse wave velocity (PWV) is most widely used for its noninvasive and easy measurement. It is well authorized that information on arterial stiffness is associated with the development of future cardiovascular events, independent from traditional cardiovascular risk factors, in various patient groups with specific diseases along with the general population. Moreover, when this information of arterial stiffness is associated with other risk stratification tools, it is possible to predict individuals' cardiovascular risk easier. Herein, we will review the incremental value of the measurement of arterial stiffness in cardiovascular risk assessment when combined with other risk factors such as traditional risk factors, biomarkers, other vascular testing and non-invasive cardiac imaging.

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New indices of arterial stiffness correlate with disease severity and mid-term prognosis in acute decompensated heart failure

Cited by 3 publications

References 36 publications

A Noninvasive Arterial Stiffness Index to Estimate the Severity of Coronary Atherosclerosis in Patients Undergoing Coronary Angiography

A Noninvasive Arterial Stiffness Index to Estimate the Severity of Coronary Atherosclerosis in Patients Undergoing Coronary Angiography

Arterial Stiffness and Cardiovascular Risk: The Role of Brachial Cuff-measured Index

Incremental value of the measures of arterial stiffness in cardiovascular risk assessment

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