New Haven survey of joint diseases

Acheson, R. M.; Chan, Yick‐Kwong

doi:10.1016/0021-9681(69)90050-2

Cited by 47 publications

(2 citation statements)

References 14 publications

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“…Rheumatoid arthritis usually results in worse symptoms in the morning 35 , 36 , 37 and lower pain intensities in the late afternoon. 26 , 27 , 38 A link to pain and secretion of cortisol 39 , 40 and melatonin 41 , 42 , 43 has been found.…”

Section: Resultsmentioning

confidence: 99%

Circadian pain patterns in human pain conditions – A systematic review

et al. 2022

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Background Chronobiology is the science of how physiological processes in the body follow a pattern of time. Pain has been shown to follow a circadian rhythm, with different types of pain having variable expression along this rhythm. Objective This article reviews the nature of diurnal variations in pain along with a discussion of the mechanisms of circadian rhythm of pain. Evidence Review We conducted a literature search on the PubMed and Google Scholar electronic databases, through April 2022. Publications were screened for English language, full‐text availability, and human subjects. Randomized controlled trials and observational trials were included. Data were extracted from studies on patients with acute or chronic pain phenotypes, which provide pain severity data and corresponding diurnal time points. Findings The literature search led to the inclusion of 39 studies. A circadian pattern of pain was found to be present in nociceptive, neuropathic, central, and mixed pain states. Postoperative pain, fibromyalgia, trigeminal neuralgia, and migraines were associated with higher pain scores in the morning. Temporomandibular joint pain, neuropathic pain, labor pain, biliary colic, and cluster headaches increased throughout the day to reach a peak in the evening or night. Arthritis and cancer pain were not associated with any circadian rhythmicity. Furthermore, the circadian rhythm of pain was not found to be altered in patients on analgesics. Conclusion The results of this review suggest that an understanding of diurnal variation may help improve therapeutic strategies in pain management, for instance through analgesic titration.

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Section: Resultsmentioning

confidence: 99%

Circadian pain patterns in human pain conditions – A systematic review

et al. 2022

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“…Variables influencing SU such as age and BMI have been suggested to contribute more to variation in SU in women (20%) than men (9%) 16 . The major factor thought to account for the observed gender differences is the female hormone profile.…”

Section: Biomarker Criteriamentioning

confidence: 99%

Serum Urate in Chronic Gout — Will It Be the First Validated Soluble Biomarker in Rheumatology?

Stamp¹,

Khanna²,

Dalbeth³

et al. 2011

J Rheumatol

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Objective To summarize evidence for and endorsement of serum urate (SU) as having fulfilled the OMERACT filter as a soluble biomarker in chronic gout at the 2010 Outcome Measures in Rheumatology Meeting (OMERACT 10). Methods Data were presented to support the use of SU as a soluble biomarker in chronic gout and specifically the ability to utilize it to predict future patient-reported outcomes. Results SU was accepted as having fulfilled the OMERACT filter by 78% of voters. However, consensus was not obtained regarding its use as a soluble biomarker in chronic gout. Although the majority of the criteria for a soluble biomarker were fulfilled, the key criterion of association of the biomarker with outcomes was not agreed upon. It was agreed that the appropriate choice of endpoint must be linked to its clinical importance to the individual with the disorder and its temporal relationship to the intervention. Appropriate outcomes in chronic gout may therefore include gout flares, reduction in tophi, and patient-reported outcomes. Conclusion SU is a critical outcome measure. It has the potential to fulfil criteria for a soluble biomarker. Further analyses of existing data from randomized controlled trials will be required to determine whether SU can predict future important outcomes, in particular disability.

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Correlates and Consequences of Asymptomatic Hyperuricemia

Fessel¹

1973

Arch Intern Med

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New Haven survey of joint diseases

Cited by 47 publications

References 14 publications

Circadian pain patterns in human pain conditions – A systematic review

Circadian pain patterns in human pain conditions – A systematic review

Serum Urate in Chronic Gout — Will It Be the First Validated Soluble Biomarker in Rheumatology?

Correlates and Consequences of Asymptomatic Hyperuricemia

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