New Generation Drug-Eluting Stents Implantation in Patients With Chronic Kidney Disease

Toutouzas, Konstantinos; Patsa, Chrysoula; Tsioufis, Costas; Tsiamis, Eleftherios; Spanos, Anastasios; Tentolouris, Costas; Tousoulis, Dimitrios; Stefanadis, Christodoulos

doi:10.1016/s0735-1097(10)61994-8

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“…Although many studies have shown that chronic kidney disease (CKD) is related to cardiovascular disease, there is still some controversy about whether CKD has an impact on the prognosis of patients with myocardial infarction undergoing PCI. [14][15][16] Therefore, this study proposes to adopt a meta-analysis method to compare the incidence of MACEs after PCI in myocardial infarction patients with CKD and non-CKD and to analyze the relationship between CKD and the prognosis of PCI to provide a basis for improving the prognosis of PCI in the clinic.…”

Section: Introductionmentioning

confidence: 99%

Effect of glomerular filtration rate in patients undergoing percutaneous coronary intervention: A systematic review and meta-analysis

et al. 2022

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Background: Through meta-analysis of the relationship between glomerular filtration rate and major adverse cardiovascular events (MACE) after percutaneous coronary intervention (PCI), we studied the impact of glomerular filtration rate on the prognosis of PCI.Methods: We collected literature on the incidence of MACE in patients with chronic kidney disease (CKD; estimated glomerular filtration rate < 60 mL/minute/1.73 m 2 ) and patients with nonchronic kidney disease undergoing PCI. The search period was from January 1, 2000, to November 1, 2021. The searched databases included CNKI, Chinese Wanfang Data, China Biology Medicine disc, Web of Science, PubMed, and Cochrane Library. We used subgroup analysis and meta-regression to assess heterogeneity.Results: Twenty-one eligible studies were included, with 46,255 samples included, 4903 cases of MACE (10.6%), and patients with CKD had a higher risk of MACE after PCI (Risk ratios = 1.67; 95% confidence interval: 1.51-1.85). Multivariate meta regression results show that heterogeneity is related to region. The risk of MACEs in patients with CKD is different in different regions, and North America has the lowest risk, with an risk ratios value of 1.21 (95% confidence interval: 1.08-1.35).Conclusion: Chronic kidney disease will increase the probability of MACE in patients with myocardial infarction after PCI and affect the prognosis of PCI. Therefore, clinical attention should be given to assessing glomerular filtration rate effects while treating patients with myocardial infarction with the PCI procedure.Abbreviations: CI = confidence interval, CKD = chronic kidney disease, eGFR = estimated glomerular filtration rate, MACE = major adverse cardiovascular events, PCI = percutaneous coronary intervention, RR = risk ratios.

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Section: Introductionmentioning

confidence: 99%