New gem-difluoromethylene-containing isocyanide as a useful building block for the synthesis of difluorinated pseudopeptides via Ugi reaction

Photoluminescence and labelling for microcrack bone of N-salicylidene-3-amino-1,2,4-triazole

“…As one of the most important fluorescent compounds, Schiff bases have received considerable attention during the past decades [5][6][7] due to their good biological activities [8,9] and photoluminescent properties [10,11]. The salicylidene N-heterocycle derivatives can exhibit different emission bands due to their reversible photo-, thermo-or solvato-induced cis/transenol/keto isomerization reactions that involve an intramolecular proton transfer from the o-hydroxy group of enol tautomer to the imino nitrogen atom of keto tautomer (Scheme 1).…”

Synthesis and luminescence properties of novel 4-(N-carbazole methyl) benzoyl hydrazone Schiff bases

“…Since the Schiff bases possess strong coordination abilities [1,2], various coordination forms [3,4], good biological activities [5,6] and fluorescence properties [7,8], the synthesis and physical and chemical properties of the acylhydrazones Schiff bases have received considerable attention during the past decades [9][10][11]. Schiff base derivatives incorporating a fluorescent moiety are an appealing tool for optical sensing of metal ions [12].…”

Novel synthesis of pseudopeptides bearing a difluoromethyl group by Ugi reaction and desulfanylation

“…Various fluorinated building blocks have been used in the Ugi four-component reaction to construct a fluorinated compound library [ 22 – 25 ]. Our group has always been interested in developing efficient methods for the preparation of difluoromethyl-containing compounds through multicomponent reactions [ 26 – 30 ]. Recently, we reported a novel and general strategy for the construction of a difluoromethyl compound library, and we further illustrated this strategy by application to the synthesis of CF 2 H-bearing pseudopeptides and 1,2,3-triazoles through Ugi and click reaction, respectively [ 27 , 30 ].…”