New Frontiers in Brachytherapy

Nag, Subir

doi:10.1016/s1055-3207(18)30136-4

Cited by 2 publications

(2 citation statements)

References 24 publications

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“…In high dose rate (HDR) brachytherapy, the radioactive source must be advanced accurately, according to the treatment plan, to ensure that the prescribed dose is delivered (Nag 2000). Brachytherapy treatment is susceptible to errors due to mismatched catheter lengths, variation of the source positions and dwell times (Duan et al 2003, Sheikh-Bagheri andMunro 1998).…”

Section: Introductionmentioning

confidence: 99%

Real-time verification of HDR brachytherapy source location: implementation of detector redundancy

et al. 2005

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Independent treatment verification for high dose rate (HDR) brachytherapy is needed to ensure that the treatment proceeds as prescribed. In this paper, we investigate the feasibility of a proposed real-time source position verification process. This process provides immediate confirmation of the source position during the treatment, so that the treatment can be aborted and modified if necessary. We show that an array of dosimeters placed on the patient's skin can independently verify the position in three dimensions. This verification was demonstrated by using a diamond detector placed in several locations on the surface of an anthropomorphic phantom. A mathematical algorithm was constructed to estimate the location of the source given a measured data set in the presence of tissue heterogeneity. The accuracy of the source localization was found to increase with the number of detectors used to compute the estimation of the source position. The resolution to which the 12 detectors can identify the location of the source was within 3 mm.

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Section: Introductionmentioning

confidence: 99%

Real-time verification of HDR brachytherapy source location: implementation of detector redundancy

et al. 2005

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“…The brachytherapy control computer and associated hardware (the remote afterloader) are used to drive the source to locations inside the catheters as determined by the planning system. Accurate dose delivery to the target volume depends on accurate placement of the catheter and correct propagation of the source in the catheter (Nag 2000). Treatment errors can occur from incorrect placement of the source resulting from, for example, a mismatched catheter length, variation in the source position, malfunction of the remote afterloading systemand inaccuracy of the treatment set-up.…”

Section: Introductionmentioning

confidence: 99%

High dose-rate brachytherapy source localization: positional resolution using a diamond detector

et al. 2003

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A potential real-time source position verification process for high dose-rate (HDR) brachytherapy treatment is described. This process is intended to provide immediate confirmation that a treatment is proceeding according to plan, so that corrective action can be taken if necessary. We show that three dosimeters are in principle sufficient and demonstrate the feasibility of the process using a diamond detector and an Ir-192 source. An error analysis including all identified sources of error shows that this detector is capable of locating the distance to the source to within 2 mm for distances up to 12 cm. This positional accuracy is less than the diameter of typical HDR catheters indicating that a diamond detector can be used to accurately determine the distance to the source. The uncertainty in the distance is found to increase with distance.

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New Frontiers in Brachytherapy

Cited by 2 publications

References 24 publications

Real-time verification of HDR brachytherapy source location: implementation of detector redundancy

Real-time verification of HDR brachytherapy source location: implementation of detector redundancy

High dose-rate brachytherapy source localization: positional resolution using a diamond detector

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