“…1 Development of e¤cient, mild and reliable reagents for this propose has been an objective of synthetic chemists and over the years a large number of such reagents have been reported, e.g. Sulfuryl chloride £uoride, 2 chlorosulfonyl isocyanate, 3 diphosphorus tetraiodide, 4 1,1 H -dicarbonylbisimidazole, 5 chlorothionoformate, 6 trimethylamine^sulfur dioxide complex, 7 phosphonitrilic chloride, 8 titanium chloride^pyridine, 9 dialkyl hydrogenphosphonate, 10 ortho ester^acid catalyst, 11 polymer supported triphenyl-phosphine^carbon tetrachloride, 12 N-tri£uoroacetylimidazole, 13 2-methylthio-4,6-diphenyl-pyrylium tetra-£uoroborate^triethylamine, 14 1-chlorosul¢nyl-4-dimethylaminopyridinium chloride, 15 carbon disul¢de^phase transfer catalyst, 16 , CsX^zeolite, 17 , montmorillonite-KSF, 18 , 1,1 Hcarbonyldibenzotriazole, 19 envirocat EPZG, 20 sulfuric acid^silica gel, 21 N,N H -sul¢nylbisimidazole 22 and di-2pyridyl sul¢te. 23 Each method using the above reagents encounters at least one of the following drawbacks: (1) long reaction times, (2) unsatisfactory yields, (3) harsh reaction conditions, (4) expensive or not readily available reagents, (5) inconvenient preparation of reagents, (6) need for addition of an acid or a base, (7) need of a phase transfer catalyst, (8) high reaction temperature, (9) tedious work-up procedures, or (10) limited adaptability both to aryl and alkyl substituted aldoximes.…”