In the western flank of the North Anatolian Fault restraining bend (i.e., Central Pontides), the Filyos River incises through the uplifting Karabük Range, creating the~1.7-km-deep Filyos River Gorge on the hanging wall of the reverse Karabük Fault. Seven fluvial strath terrace levels are preserved in this gorge. optically stimulated luminescence ages from quartz-rich sediments of five terrace levels reveal an average long-term rock uplift rate of 0.45 ± 0.02 mm yr −1 with an unsteady pattern of uplift during the last 542 ± 24 kyr. Uplift rates of 1.52 ± 0.6 and 0.74 ± 0.3 mm yr −1 occurred before 366 ± 19 kyr, followed by lower rates of~0.1 and 0.31 mm yr −1 through present. These later uplift rates may reflect relatively slower tectonic rates since~366 kyr, with closer similarity to regional uplift rates of~0.3 mm yr −1 yielded from the eastern flank of the Central Pontides. The Karabük Range fluvial terraces are near the North Anatolian Fault, meaning pre-~366 kyr uplift rates may be a glimpse of the highest Central Pontides Quaternary rock uplift rates on uplifting hanging wall blocks activated by the restraining bend. When we consider offshore seismic reflection data, the focal mechanism solution of the Bartın Earthquake, onshore structural data, and regional tectonic geomorphology, the western flank of the Central Anatolian Plateau's northern margin is propagating northward as a growing orogenic wedge with a positive flower-structure geometry. Plain Language Summary In north central Turkey, the northern bend of the North Anatolian fault causes uplift (i.e., Central Pontides), the Filyos River incises vertically into the uplifting topography, creating a 1.7-km-deep gorge west of the Karabük Fault. Seven river terrace levels were preserved, representing former elevations of the Filyos River. The optically stimulated luminescence technique was used to estimate the ages of these terraces, revealing a rate of vertical river incision into uplifting topography. This yielded a long-term rock uplift rate of~0.45 mm yr −1 (~45 cm kyr −1) since around 540 kyr. However, the pattern was unsteady, with uplift rate periods of~1.52 and~0.74 millimeters per year until 366 thousand years ago, then lower rates of~0.1 and 0.31 mm yr −1 through present. These later uplift rates may indicate weaker tectonics in the area compared to before, while they are also similar to regional rates measured farther east. The uplift rates before 366 kyr on the uplifting side of the Karabük Fault may be a glimpse of some of the higher uplift rates in the Central Black Sea region of Turkey.