“…There are several reports in the literature describing the tetrahydronaphthalene derivatives for their various pharmacological activities, including action as nonsteroidal glucocorticoid receptor modulators (5) , anticancer (6)(7)(8) , antimicrobial (9) , antifungal (10) and anti-HIV (11,12) . The thiazolidinones ring with C-2 and N-3 substituted positions has been incorporated into a broad range of known biologically active compounds as antimicrobial (13) , anti-inflammatory (14) , anticancer and antiviral activity (15) .…”