New Drug Design to Suppress Nonalcoholic Steatohepatitis
Soykan Agar,
Barbaros Akkurt,
Engin Ulukaya
Abstract:A de novo designed biomolecule called INASHD was utilized through computer-aided drug design techniques to specifically target β2-spectrin, effectively suppressing and preventing NASH disease. Advanced computational software tools concerning the technologies of molecular docking and molecular dynamics (MD), were employed to showcase the drug's remarkable ability to efficiently suppress and control the α-helical topology of β2-spectrin. This protein is a vital component within the disease pathway. We successful… Show more
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