New Directions in Training Designs

Cochrane, Aaron; Green, C. Shawn

doi:10.1007/978-3-030-39292-5_3

Cited by 5 publications

(2 citation statements)

References 55 publications

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“…Therefore, especially mobile computerized CT (cCT) is proposed as a treatment option as it can be accessed via smartphone and provide convenient, self-administered, non-invasive, and personalized treatment that can be applied anywhere for example in the safe and discrete home environment, thereby overcoming some of the existing barriers [16]. The gami ed and tailored approach of cCT is accompanied by higher motivation and more consistent training adherence [17]. The shift from traditional paper-pencil-CT to cCT has been evident over the past years leading to rapid growth of publicly available brain training software [18].…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of mobile computerized cognitive training in adults with mild cognitive impairment: interim analysis of a randomized controlled trial

Ferizaj,

Stamm,

Perotti

et al. 2024

Preprint

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Computerized cognitive training (cCT) is recommended as standard therapy for patients with mild cognitive impairment (MCI). While traditional cognitive training involves long waiting times, mobile cCT can efficiently improve the healthcare situation. This interim analysis of the ongoing NeuroNation MED Effectiveness Study (NeNaE) aims to assess first effects of a mobile, gamified cCT (NeuroNation MED) in participants with MCI. In the intention-to-treat analysis, the intervention group (IG) performed 12 weeks of training with the NeuroNation MED app, while the control group (CG) represented a waiting group. This interim analysis included 50 participants (IG: n = 36; CG: n = 14). As primary outcome, we examined the index score of the Neuropsychological Assessment Battery Screening Module (S-NAB). Alpha spending results in an alpha level of .00305 for the interim analysis. This analysis showed first positive evidence for the effectiveness of the intervention where the IG improved significantly in the S-NAB index score (t(35) = 3.17, p = 0.0028, Cohen's d = 0.53). However, ANCOVA revealed no significant group differences between IG and CG in the S-NAB index score (F(1, 47) = 5.39, p = 0.025, ηp2 = 0.125). Additionally, the IG showed a significant mean decrease in subjective memory measured with the CFQ-D (MD = - 10.56, SD = 18.82, t(35)= 3.21, p = 0.0029, Cohen's d = 0.53). Conducting the complete study is crucial to determine the effectiveness of NeuroNation MED. Clinical Trial Registration ID DRKS00025133 Date of registration: 05.11.2021

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Section: Introductionmentioning

confidence: 99%

Effectiveness of mobile computerized cognitive training in adults with mild cognitive impairment: interim analysis of a randomized controlled trial

Ferizaj,

Stamm,

Perotti

et al. 2024

Preprint

View full text Add to dashboard Cite

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“…These cCT programs offer several advantages over traditional paper-pencil tasks, including enhanced interactivity, adaptability, accessibility, motivation, and adherence [29]. Moreover, these programs offer personalized training tailored to individual needs and strengths [27,[30][31][32][33]. Furthermore, cCT can be conveniently delivered via smartphone or tablet, allowing for home-administered training.…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of a mobile application for independent cognitive training in patients with mild cognitive impairments: Study protocol for the NeNaE Study, a randomized controlled trial

Ferizaj,

Stamm,

Perotti

et al. 2023

Preprint

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Background:Mild Cognitive Impairment (MCI) involves cognitive decline beyond typical age-related changes, but without significant daily activity disruption. It can encompass various cognitive domains as the causes of MCI are diverse. MCI as well as frequent comorbid neuropsychiatric conditions like depression and anxiety affect individuals' quality of life. Early interventions are essential, and computerized cognitive training (cCT) is an established treatment method. This paper presents the protocol for the NeuroNation MED Effectiveness Study, evaluating the self-administered mobile cCT intervention ("NeuroNation MED") in individuals with MCI to assess training effects on cognitive domains, health competence, neuropsychiatric symptoms, psychological well-being, and the general application usability. Methods:This study protocol presents a single-blinded multicenter randomized controlled trial that will be carried out in six study centers in Germany and Luxembourg. We included adults with MCI (existing F06.7 ICD-10-GM diagnosis and TICS ≥21 and ≤ 32). The intervention group will use a mobile, multi-domain cCT (“NeuroNation MED”) for 12 weeks. Meanwhile, the wait list control group will receive standard medical care or no care. The eligibility of volunteers will be determined through a telephone screening. After completion of the baseline examination, patients will be randomly assigned to one of the experimental conditions in a 2:1 ratio. In total, 286 participants will be included in this study. The primary outcome is the change of cognitive performance measured by the index score of the screening module of the Neuropsychological Assessment Battery. Secondary outcomes are changes in the Cognitive Failures Questionnaire, Hospital Anxiety and Depression Scale, Health-49, Health Literacy Questionnaire, among others. All of the primary and secondary outcomes will be assessed at baseline and after the 12-week post-allocation period. Furthermore, the intervention group will undergo an assessment of the System Usability Scale, and the training data of the NeuroNation MED application will be analyzed. Discussion:This study aims to assess the effectiveness of a mobile self-administered cCT in enhancing cognitive abilities among individuals diagnosed with MCI. Should the findings confirm the effectiveness of the NeuroNation MED app, it may confer possible benefits for the care management of patients with MCI, owing to the accessibility, cost-effectiveness, and home-based setting it provides. Specifically, the cCT program could provide patients with personalized cognitive training, educational resources, and relaxation techniques, enabling participants to independently engage in cognitive training sessions at home without further supervision. Trial registration: German Clinical Trials Register (DRKS00025133). Date of registration: 5 November 2021.

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Multitasking Training

Karbach

Strobach

2022

Handbook of Human Multitasking

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New Directions in Training Designs

Cited by 5 publications

References 55 publications

Effectiveness of mobile computerized cognitive training in adults with mild cognitive impairment: interim analysis of a randomized controlled trial

Effectiveness of mobile computerized cognitive training in adults with mild cognitive impairment: interim analysis of a randomized controlled trial

Effectiveness of a mobile application for independent cognitive training in patients with mild cognitive impairments: Study protocol for the NeNaE Study, a randomized controlled trial

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