New diamidequat-type surfactants in fabrication of long-sustained theranostic nanocapsules: Colloidal stability, drug delivery and bioimaging

Two-Photon Induced Fluorescence Energy Transfer in Polymeric Nanocapsules Containing CdSexS1–x/ZnS Core/Shell Quantum Dots and Zinc(II) Phthalocyanine

“…The nanocapsules were prepared via solvent/emulsification method. This technique is a three-step process, which allows for high co-encapsulation efficiency of hydrophobic therapeutic and/or diagnostic compounds in oil core microenvironment of a nanocarriers 2,[26][27][28][29] . Poloxamer 403 was applied as the polymer component; Cremophor EL ® as the nonionic surfactant and silicone oil with hydrogenated caprylyl olive oil esters as the oil phase.…”

Architectures and Mechanical Properties of Drugs and Complexes of Surface-Active Compounds at Air-Water and Oil-Water Interfaces

“…Similar possibilities exist for pharmaceutical foams [12], although they are much less commonly used. However, dispersions of solids covered with functional polymers do present a huge opportunity for significant improvement to current practice and chances for revolutionary, life-changing new products [27,56].…”

“…Dissolution or partdissolution of the array of interactions between and within complex hetero-polymer molecule networks, such as adsorbed proteins and nucleotides is entirely feasible. Therefore, it is possible to engineer the properties of therapeutic foams and emulsions [5,8,11,12,16,20,22,43,45,47,55] by using complementary mixes of amphiphilic soft matter assemblies and solid suspensions to 'house' drug in the adsorbed layer, which adds another possibility for the notions of a controlled release of drug, particle loading with therapeutics, encapsulation [10,16,39,45,46,47] of valuable species and also for housing quantum dots and plasmon generating nanoparticles for diagnostic medical uses described at length by Bazylińska et al [56].…”

“…3-5), and combination systems with bifunctional agents ( Figs. 6-9), used as the basis of understanding less frequently studied drugsurfactant interactions [8,10,20,43,44,51,56], which show promise and significant interfacial behavior [4,18,35,38,50] that can be utilized in various foam and emulsion systems. More importantly, a clearer understanding of pharmaceutical and vaccine dispersion interfacial properties, is made possible by consideration of better understood interfacial behavior ( Figs.…”

“…13), analogous to a twodimensional gel. The interaction can be diverse or simple, usually being complex, where proteins and hetero-polymers or drugs with multiple functional groups are concerned [3,6,41,56]. There is and has been considerable debate [33,40,41] as to the form of such an adsorbed layer, which may change from a simple monolayer to multiple layers or strata, with varying degrees and depths of entanglement and interconnection (Fig.…”