New Developments in the Synthesis of Anisomycin and Its Analogues

Nemr, Ahmed El; Ashry, E. S. H. El

doi:10.1007/7081_2007_051

Cited by 8 publications

(4 citation statements)

References 80 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Down-hole tubules, flow lines, and transmission pipelines are all made of carbon steel (CS) [11][12][13][14][15]. However, in corrosive conditions such as those found in the oil industry, CS has poor corrosion resistance [16][17][18][19][20]. Some of the most frequent techniques of regulating corrosion rate in acid solutions in oil operations include pickling, industrial acid cleaning, oil and gas well acidizing, and removing rust, scale, and corrosion elements [21][22][23][24], using corrosion inhibitors.…”

Section: Introductionmentioning

confidence: 99%

Camphor tree bark extract as green corrosion inhibitor of LCS in 0.5 M H₂SO₄ with and without salt effect

El Nemr,

Elhebshi,

Ashour

et al. 2024

J Chinese Chemical Soc

View full text Add to dashboard Cite

This work tested the ethanol extract of camphor tree Cinnamomum camphora bark (CTBEE) as a green corrosion inhibitor of low carbon steel (LCS) in 0.5 M H2SO4 with and without the synergistic effect of 4000 ppm NaCl or 800 ppm of KI. The corrosion protection of LCS was significantly increased in the presence of CTBEE‐KI and CBWE‐NaCl blends compared with CTBEE alone, according to data performed by electrochemical impedance spectroscopy (EIS) and electrochemical polarization (EP) analyses. The formation of a film by the blends blocks the LCS surface area, preventing corrosive gradients from reaching its surface. Inhibition efficiency (IE%) of 81% and 89% were obtained in the presence of 800 ppm CTBEE‐4000 ppm NaCl and CTBEE‐800 ppm KI, respectively, compared with IE of 65% in the presence of 800 ppm CTBEE only. A maximum IE% of 89% and 97% were reached after 72 h of immersion in the presence of CTBEE‐NaCl and CTBEE‐KI, respectively. Potentiodynamic experiments indicate that the blends act as mixed‐type inhibitors. The inhibition efficiency of CTBEE, CTBEE‐KI, and CTBEE‐NaCl remained effectively high during the testing period of immersion time, which proved the excellent stability of CTBEE in the corrosive acidic media.

show abstract

Section: Introductionmentioning

confidence: 99%

Camphor tree bark extract as green corrosion inhibitor of LCS in 0.5 M H₂SO₄ with and without salt effect

El Nemr,

Elhebshi,

Ashour

et al. 2024

J Chinese Chemical Soc

View full text Add to dashboard Cite

show abstract

“…For instance, in India, the leather tanning industries processing caused a high influent of (2000 ~ 32,000 tons/year of Cr 6+ ) on the environment 8 , 9 . Also, chromium is used extensively in electroplating, chromic acid, drilling muds, catalytic reagents and refractory steel 10 .…”

Section: Introductionmentioning

confidence: 99%

Formation of self-nitrogen-doping activated carbon from Fish/sawdust/ZnCl2 by hydrothermal and pyrolysis for toxic chromium adsorption from wastewater

El‐Nemr

Hassaan

Ashour

2023

Sci Rep

View full text Add to dashboard Cite

This study gives a description of the formation of self-nitrogen doped activated carbon (NDAC) by a novel way of employing fish meal (mixture of Atherina hepseetus and Sardina pilchardus of 60% protein) as nitrogen dopant, ZnCl2 as impregnate agent, sawdust as carbon source and water with a mass ratio (2:1:1:12), which subjected to the hydrothermal process. The hydrothermal mixture was oven dried and carbonized under a flow of nitrogen for one h at 600, 700, and 800 °C. The characterization of NDAC was performed by using various analytical techniques analyses. The synthesized NDAC exhibited unique features such as microporous structure (1.84 ~ 2.01 nm), high surface area (437.51 ~ 680.86 m2/g), the volume of total pores (0.22 ~ 0.32 cm3/g) and nitrogen content (12.82 ~ 13.73%). Batch removal tests were achieved to investigate the impact of chromium ions starting concentration (100–400 mg/L), NDAC dose (0.5–2.5 g/L), pH and contact time (5–120 min). Such helpful characteristics of NDAC, particularly for NDAC600, were suitable to use as an excellent adsorbent for Cr6+ ions with a maximum adsorption capacity (Qm) (769.23 mg/g), and the highest chromium ions adsorption uptake (81.18%) was obtained at pH value 1.5 at room temperature. Both Halsey and Temkin models fitted the adsorption data quite reasonably. The uptake of toxic chromium ions is best represented with pseudo-second-order rate kinetics data.

show abstract

“…Interest in anisomycin has led to various syntheses of the densely functionalized chiral pyrrolidine structure and derivatives using a variety of starting materials, such as various carbohydrate and amino acid precursors [ 14 ]. Early studies of relationships between anisomycin structure and activity on protein translation demonstrated that removal of the 3-position acetoxy group (desacetylanisomycin, 2 ), nitrogen acetylation and quaternization, as well as aromatic bromination, all resulted in analogs (e.g., 3 – 5 ) exhibiting significant reductions of activity [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Systematic Exploration of Functional Group Relevance for Anti-Leishmanial Activity of Anisomycin

Nguyen,

Shalev-Benami,

Rosa-Teijeiro

et al. 2023

Biomedicines

View full text Add to dashboard Cite

Assessment of structure–activity relationships for anti-protozoan activity revealed a strategy for preparing potent anisomycin derivatives with reduced host toxicity. Thirteen anisomycin analogs were synthesized by modifying the alcohol, amine, and aromatic functional groups. Examination of anti-protozoal activity against various strains of Leishmania and cytotoxicity against leucocytes with comparison against the parent natural product demonstrated typical losses of activity with modifications of the alcohol, amine, and aromatic meta-positions. On the other hand, the para-phenol moiety of anisomycin proved an effective location for introducing substituents without significant loss of anti-protozoan potency. An entry point for differentiating activity against Leishmania versus host has been uncovered by this systematic study.

show abstract

New Developments in the Synthesis of Anisomycin and Its Analogues

Cited by 8 publications

References 80 publications

Camphor tree bark extract as green corrosion inhibitor of LCS in 0.5 M H₂SO₄ with and without salt effect

Camphor tree bark extract as green corrosion inhibitor of LCS in 0.5 M H₂SO₄ with and without salt effect

Formation of self-nitrogen-doping activated carbon from Fish/sawdust/ZnCl2 by hydrothermal and pyrolysis for toxic chromium adsorption from wastewater

Systematic Exploration of Functional Group Relevance for Anti-Leishmanial Activity of Anisomycin

Contact Info

Product

Resources

About

New Developments in the Synthesis of Anisomycin and Its Analogues

Cited by 8 publications

References 80 publications

Camphor tree bark extract as green corrosion inhibitor of LCS in 0.5 M H2SO4 with and without salt effect

Camphor tree bark extract as green corrosion inhibitor of LCS in 0.5 M H2SO4 with and without salt effect

Formation of self-nitrogen-doping activated carbon from Fish/sawdust/ZnCl2 by hydrothermal and pyrolysis for toxic chromium adsorption from wastewater

Systematic Exploration of Functional Group Relevance for Anti-Leishmanial Activity of Anisomycin

Contact Info

Product

Resources

About

Camphor tree bark extract as green corrosion inhibitor of LCS in 0.5 M H₂SO₄ with and without salt effect

Camphor tree bark extract as green corrosion inhibitor of LCS in 0.5 M H₂SO₄ with and without salt effect