New Copolymers of Vinylphosphonic Acid with Hydrophilic Monomers and Their Eu3+ Complexes

Назарова, О. В.; Chesnokova, E. B.; Nekrasova, T. N.; Zolotova, Yu. I.; Добродумов, А. В.; Vlasova, E. N.; Fischer, A. I.; Безрукова, М. А.; Panarin, E. F.

doi:10.3390/polym14030590

Cited by 3 publications

(1 citation statement)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The syntheses of VPA copolymers with 2-deoxy-2-methacrylamido-D-glucose, 4-acryloylmorpholine, or acrylamide, were the subject of the recent study of Nazarova and Coll. [ 102 ]. The reactions were conducted in DMF or MeOH (AIBN initiator) or aqueous media (AIBA initiator).…”

Section: Design and Synthesis Of Sidechain Pcpasmentioning

confidence: 99%

Design, Synthesis and Actual Applications of the Polymers Containing Acidic P–OH Fragments: Part 2—Sidechain Phosphorus-Containing Polyacids

Nifant’ev

Ivchenko

2023

IJMS

View full text Add to dashboard Cite

Macromolecules containing acidic fragments in side-groups—polyacids—occupy a special place among synthetic polymers. Properties and applications of polyacids are directly related to the chemical structure of macromolecules: the nature of the acidic groups, polymer backbone, and spacers between the main chain and acidic groups. The chemical nature of the phosphorus results in the diversity of acidic >P(O)OH fragments in sidechain phosphorus-containing polyacids (PCPAs) that can be derivatives of phosphoric or phosphinic acids. Sidechain PCPAs have many similarities with other polyacids. However, due to the relatively high acidity of –P(O)(OH)2 fragment, bone and mineral affinity, and biocompatibility, sidechain PCPAs have immense potential for diverse applications. Synthetic approaches to sidechain PCPAs also have their own specifics. All these issues are discussed in the present review.

show abstract

Section: Design and Synthesis Of Sidechain Pcpasmentioning

confidence: 99%

Design, Synthesis and Actual Applications of the Polymers Containing Acidic P–OH Fragments: Part 2—Sidechain Phosphorus-Containing Polyacids

Nifant’ev

Ivchenko

2023

IJMS

View full text Add to dashboard Cite

show abstract

One-pot synthesis of novel polyvinylphosphonic acid hydrogels for efficient separation of low-enriched uranium in water

Liang,

Tian,

Wang

et al. 2024

Journal of Molecular Liquids

View full text Add to dashboard Cite

Synthesis and Anti-influenza Activity of Vinylphosphonic Acid (Co)polymers

Zarubaev

Buchkov²,

Назарова³

et al. 2022

Dokl Biochem Biophys

View full text Add to dashboard Cite

New copolymers of vinylphosphonic acid (VPA) with 2-deoxy-2-methacrylamido-D-glucose, 4-acryloylmorpholine (4-AM), and acrylamide have been synthesized, and their antiviral activity against influenza virus has been studied in in vitro and in vivo experiments. Optimal antiviral characteristics and low cytotoxicity were exhibited by the copolymer of VPA with 4-AM, composition 56 : 44 mol %, molecular weight 33000. The polymer exhibited virus-inhibiting properties with an IC 50 = 1 μg/mL and a selectivity index of 302. Prophylactic intranasal administration of the polymer in a murine model of influenza pneumonia completely prevented the virus-induced death of animals, whereas the level of mortality in the placebo group was 90%. The results of this study indicate a high antiviral potential of polymeric compounds based on VPA.

show abstract

New Copolymers of Vinylphosphonic Acid with Hydrophilic Monomers and Their Eu3+ Complexes

Cited by 3 publications

References 33 publications

Design, Synthesis and Actual Applications of the Polymers Containing Acidic P–OH Fragments: Part 2—Sidechain Phosphorus-Containing Polyacids

Design, Synthesis and Actual Applications of the Polymers Containing Acidic P–OH Fragments: Part 2—Sidechain Phosphorus-Containing Polyacids

One-pot synthesis of novel polyvinylphosphonic acid hydrogels for efficient separation of low-enriched uranium in water

Synthesis and Anti-influenza Activity of Vinylphosphonic Acid (Co)polymers

Contact Info

Product

Resources

About