New concepts of integrated photonic biosensors based on porous silicon

Li, Cheng; Gerelli, Emmanuel; Orobtchouk, Régis; Benyattou, T.; Belarouci, Ali; Chevolot, Yann; Monnier, Virginie; Souteyrand, Éliane; Jamois, Cécile

doi:10.5772/17197

Cited by 5 publications

(5 citation statements)

References 71 publications

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“…The photonic crystal was simulated as top and bottom distributed Bragg reflectors (DBRs), each consisting of three pairs of alternating layers with a high and a low porosity (82 and 57%, respectively). The pSi layers have been simulated as homogeneous layers with the effective refractive indices predicted by Bruggeman's effective medium model 7,8 . Specifically, the high and low porosity layers had refractive indices of n H = 1.311 and n L = 2.138, respectively.…”

Section: Numerical Simulation Of Hierarchical Plasmon-optical Cavitie...mentioning

confidence: 99%

Hierarchical plasmon-optical cavities based on porous silicon photonic crystals for light-matter coupling with quantum emitters

et al. 2023

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Hybrid systems based on porous silicon microcavities and quantum emitters (QEs) are of much interest in terms of both basic research and development of new hybrid photoluminescent (PL) materials to be used in photonic, optoelectronic, and sensing applications. In these systems, light-matter coupling is established, whose strength could be increased to achieve the strong coupling regime by enhancing the quality factor of the microcavity. Incorporation of plasmonic nanoparticles (PNPs) also promotes an increase in the coupling strength and establishment of the coupling regime via the formation of hierarchical plasmon-optical cavities. Here we present the results of a numerical study of hybrid systems comprising porous silicon microcavities and plasmonic arrays placed inside them. These hybrid systems enable hierarchical plasmon-optical coupling with exciton transitions in QEs embedded into a porous silicon microcavity. We used numerical simulations to estimate the critical parameters for achieving light-matter coupling, including the Purcell factor and expected field enhancement, as well as the spatial distribution of the electromagnetic field within the structure. We speculate that light-matter coupling between the PL of QEs and the hierarchical cavity mode is stronger than in a microcavity not containing PNPs.

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Section: Numerical Simulation Of Hierarchical Plasmon-optical Cavitie...mentioning

confidence: 99%

Hierarchical plasmon-optical cavities based on porous silicon photonic crystals for light-matter coupling with quantum emitters

et al. 2023

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“…129 As a result, it is helpful to rst cover the surface with a protection layer, usually deposited metal or silicon dioxide, to prevents resist from penetrating into the pores, as well as improving the surface homogeneity for subsequent resist spin-coating and photolithography. 130,131 In addition, freshly prepared PSi is easily dissolved in alkaline solution, of which most of the positive photoresist developers are made. Although the problem can be avoided by using negative photoresist and related solvent based developer, it largely limits the range of applicable photoresists and complicates the lithographic process.…”

Section: With Permission Frommentioning

confidence: 99%

“…By adjusting the experimental parameters in reactive ion etching, PSi prole with vertical sidewalls has been produced for biosensing applications. Jamois et al 43,130 developed a PSi based surface-wave biosensor via reactive-ion-etching patterning to form two-dimensional PSi multilayer structure. The surface was then functionalized by silane chemistry and immobilised with DNA probes.…”

Section: With Permission Frommentioning

confidence: 99%

Functionalised porous silicon as a biosensor: emphasis on monitoring cells in vivo and in vitro

Gupta

Zhu

Guan

et al. 2013

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Porous silicon photonics is the ideal platform for high sensitivity, high selectivity monitoring of biological molecules in a complex fluidic environment. The potential of this technology was identified almost 15 years ago, however, it has taken considerable advances in porous silicon surface chemistry, photonics, and micro-fabrication to create truly effective devices that can provide new insights into the behaviour of biological systems. In this review we provide a critical assessment of the development of porous silicon optical biosensors from the early demonstrations of affinity based sensing to the current trends in monitoring single cell activity and perspectives in the use of photonic microparticles for biomedical applications.

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“…Photonic biosensors are simple, portable, robust, and cost-effective analytical devices for the rapid and specific screening and sensitive monitoring of environmental pollutants, water, foods and beverages contaminants. Photonic biosensors combine molecular recognition elements (MREs) with optical transducer systems, which convert light rays into electronic signals, so that the specific binding of a target molecule to the MRE to be finally translated into a measurable electrical signal [ 1 , 2 , 3 ]. Aptamers are among the quite frequently used MREs in such devices for the quantification of environmental pollutants.…”

Section: Introductionmentioning

confidence: 99%

Studies towards the Synthesis of Novel 3-Aminopropoxy-Substituted Dioxins Suitable for the Development of Aptamers for Photonic Biosensor Applications

et al. 2021

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Hydroxy-substituted tetrachlorodibenzo[b,e][1,4]dioxin and tetrachlorodibenzo[b,d]furans have been synthesized using 3,4-dichloroanisole, 2,3,6-trichlorophenol and 4,5-dichlorocatechol as starting materials and electrophilic and/or nucleophilic aromatic substitution reactions for the assembly of the dibenzo[b,e][1,4]dioxin and dibenzo[b,d]furan systems. The thus-obtained phenolic compounds were then alkylated with N-1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl (Dde)-protected 3-bromopropan-1-amine to give the corresponding N-Dde protected 3-aminopropoxy-substituted tetrachlorodibenzo[b,e][1,4]dioxin and tetrachlorodibenzo[b,d]furans, respectively. Hydrazinolysis-mediated Dde removal from the former compound provided the corresponding amino-substituted dioxin, which was coupled to carboxy-substituted magnetic beads affording magnetic beads coated by the amino-substituted dioxin. The latter is an attractive intermediate for the development of selective single-standard DNA (ssDNA) aptamers, which constitute molecular recognition elements in photonic biosensors with potential application to the monitoring of the dangerous environmental pollutants, dioxins having serious implications in human health.

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New concepts of integrated photonic biosensors based on porous silicon

Cited by 5 publications

References 71 publications

Hierarchical plasmon-optical cavities based on porous silicon photonic crystals for light-matter coupling with quantum emitters

Hierarchical plasmon-optical cavities based on porous silicon photonic crystals for light-matter coupling with quantum emitters

Functionalised porous silicon as a biosensor: emphasis on monitoring cells in vivo and in vitro

Studies towards the Synthesis of Novel 3-Aminopropoxy-Substituted Dioxins Suitable for the Development of Aptamers for Photonic Biosensor Applications

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