New compounds from . X-ray crystal and molecular structures of anamarine

Isolation and relative stereochemistry of lippialactone, a new antimalarial compound from Lippia javanica

“…The proposed 5R configuration for lippialactone is in agreement with the configuration of this stereogenic centre in several other naturally occurring lactones [11,12]. It is therefore a diastereomer of synargentolide A [13] and closely related to d-lactones such as hyptolide [14], spicigerolide [15], synrotolide [16], passifloricin A [17,18], anamarine [19], and strictifolione [20]. The traditional medicinal uses of this plant [4,21] and several other Lippia species [22] are justified.…”

Efficient Synthesis of (-)-Osmundalactone and Its Epimer from Carbohydrate Precursor

“…Many natural products [1][2][3][4][5][6][7] contain lactone rings, particularly the α,β-unsaturated δ-lactone ring systems. Natural and non-natural compounds having this scaffold exhibit diverse biological activities viz.…”

Synthesis of iminosugars via 1,3-dipolar cycloaddition reactions of nitrones to α,β-unsaturated sugar aldonolactones

“…Synthesis of enantiopure a,b-unsaturated lactones An unsaturated d-lactone fragment can be found in many natural products (Fig. 3), both simple such as parasorbic acid (17) [34] and osmunda lactone (18) [35], and even structurally more complex, such as anamarine (19) [36] and boronolide (20) [37]. Butenolides (unsaturated g-lactones) [38] can also be found as fragments of many natural products (Fig.…”