New cobalt (II) complexes of '3-acetyl-4-hydroxy-2H-chromene-2-one': Crystal structure and Hirshfeld surface analysis, fluorescence behaviour and antioxidant activity

Crystal Structure, Hirshfeld Surface Analysis and Biological Activities of trans-Dipyridinebis (3-Acetyl-2-Oxo-2H-Chromen-4-Olato)Cobalt(II)

“…This effect has been observed in other cobalt(II) complexes. 21 This phenomenon is known as fluorescence quenching. The comparison of the fluorescence spectra of the coordinated complex and uncoordinated coumarin (Fig.…”

“…In the asymmetric unit of the crystal structure ( However, the angle between the equatorial plane (Co1-O1-O2) and the coumarin ligand (O1-O2-C12) is 2.67° which is smaller compared to the previously published compounds. 21 In addition, the angle between the two planes of pyridine in the axial position, plane 1 (C15/ C11/N5/C11 i /C15 i /C19) and plane 2 (C18/N4/C18 i /C17/ C13/C17 i ) with symmetry code: (ii) (-x, -y, -z) is 53.81°. In the packing of crystal lattice, all the complex molecules are connected by an extensive network of hydrogen bonds (Table 3) (Fig.…”

“…A lower IC 50 value indicates greater antioxidant activity, compared to ascorbic acid (vitamin C) as a reference that has an IC 50 value of 21 μmol/L, 44 it is considered a good free radical trapper. In addition, it possesses significant antioxidant activity relative to its coumarin ligand, 21 and other similar cobalt(II) complexes. It is difficult to draw general conclusions about antioxidant structure-activity relationships with the limited number of antioxidant molecules.…”

“…Thus, cobalt may be less toxic to the human body than other metals. 19,20 New studies are based on the investment of protocols for the synthesis of new coumarin derivatives prepared from 3-acetyl-4-hydroxycoumarin, in the form of complexes, 21 chalcones, 22,23 aminocoumarines, 24 Schiff bases, 25,26 and their complexes. 15,26 We always try to highlight them through structural studies, physical properties and Bejaoui et al: Crystal Structure, Hirshfeld Surface Analysis ... biological evaluation.…”

Synthesis, Spectroscopic and Computational Studies of Some Metals Chelates with Chromene-2-one and Pyrazine-Based Ligands

“…It is well-known from literature, the transition elements complexes with bidentate Lewis bases of coumarin have known during the last decades as antitumor agents [4][5]. As well as the semicarbazone of pyrazine derivatives with their metal chelate have adopted as active materials in the treatment of rare diseases [6][7]. The coordination chemistry of coumarin ligand has great interesting in the field of colorimetric determination of trace amounts of heavy metals [8].…”