New binuclear mercury complex: Synthesis, supramolecular structure, physico-chemical characterizations and antibacterial activity

Ltaief, Hasna; Mahroug, Adel; Azaza, Youssra Ben; Graça, M.P.F.; Belhouchet, Mohamed

doi:10.1016/j.molstruc.2021.131829

Cited by 3 publications

(2 citation statements)

References 51 publications

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“…Although mercury compounds are toxic, studies are continuing to prepare new complexes that have biological antibacterial activity [23][24][25], which encouraged studying the effectiveness of the complexes prepared in this research. Solutions of previously copper and mercury complexes, using DMSO as a solvent, were tested at three concentrations (10 -4 , 10 -3 , 10 -2 g/mol) for their biological activity employing the Agar-well diffusion method.…”

Section: Biological a Ctivitymentioning

confidence: 99%

Synthesis, Characterization, and Biological Evaluation of New Hg(II) Complexes of (2-(2-(2-chlorobenzylidene)hydrazineyl)benzothiazole with Phosphine Ligands

Ali,

Irzoqi,

Singh

2024

Tikrit J. Pure Sci.

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The Synthesis of new Hg(II) complexes of (2-(2-(2-chlorobenzylidene) hydrazinyl)benzothiazole) (CHB) with phosphine ligands (dppm, dppe, dppp, and dppb) were synthesized, resulting in complexes with the following formulas: [Hg2(CHB)2(µ-dppm)2]Cl4 or [Hg2(CHB)2(µ-phosphine)Cl2]Cl2 (where the phosphines are dppe, dppp and dppb). The suggested geometry around the metal ion is tetrahedral, with the (CHB) ligand acting as a bidentate ligand through the N atoms, while the phosphine ligands act as bidentate bridging ligands through the P atoms. The prepared complexes were characterized various analytical techniques including molar conductivity, infrared spectra, 31P{1H}-NMR, 1H-NMR, and 13C-NMR spectra. Additionally, the biological effectiveness of these complexes was evaluated against four types of bacteria, namely Streptococcus faecalis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa, has been assessed. Some of the complexes exhibited an inhibition level in the range of (5-10 mm) at the minimum inhibitory concentration indicating potential antibacteria properties.

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Section: Biological a Ctivitymentioning

confidence: 99%

Synthesis, Characterization, and Biological Evaluation of New Hg(II) Complexes of (2-(2-(2-chlorobenzylidene)hydrazineyl)benzothiazole with Phosphine Ligands

Ali,

Irzoqi,

Singh

2024

Tikrit J. Pure Sci.

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“…54 The value of Hg(II)directed materials in biological systems is also recognized. [58][59][60] Following these trends, we obtained inspiration to study the impacts of such metallogel scaffolds against pathogens. In this work, we have investigated citric acid's tendency towards metallo-gelation with Cd(II)and Hg(II)-sources in N,N-dimethyl formamide solvent under ambient conditions.…”

Section: Introductionmentioning

confidence: 99%

Two novel low molecular weight gelator-driven supramolecular metallogels efficient in antimicrobial activity applications

Dhibar,

Pal,

Karmakar

et al. 2023

RSC Adv.

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Recent trends in medicinal applications of mercury based organometallic and coordination compounds

Maqsood,

Al-Rawi,

Ibrahim

et al. 2024

Reviews in Inorganic Chemistry

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Metal-based drugs are finding new medical applications, particularly in antibacterial therapies. Compounds such as Prontosil and ciprofloxacin, as well as its derivatives such as beta-lactam drugs, aminoglycosides, vancomycin, fosfomycin, as well as tetracyclines, play critical roles in the prevention of bacterial and fungal infections. The increasing prevalence of microbial resistance is prompting the use of metal complexes to tackle fungal and bacterial strains. Mercury-based complexes, which are known for their unusual characteristics and reactivity, have received a lot of interest in the field of medicine recently. Additionally, Schiff base complexes are widely used as antifungal, antibacterial, and anticancer drugs, as well as in dye manufacturing. This article discusses current advances in the use of mercury compounds for combating fungus and bacteria, offering information on their efficacy and future applications.

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New binuclear mercury complex: Synthesis, supramolecular structure, physico-chemical characterizations and antibacterial activity

Cited by 3 publications

References 51 publications

Synthesis, Characterization, and Biological Evaluation of New Hg(II) Complexes of (2-(2-(2-chlorobenzylidene)hydrazineyl)benzothiazole with Phosphine Ligands

Synthesis, Characterization, and Biological Evaluation of New Hg(II) Complexes of (2-(2-(2-chlorobenzylidene)hydrazineyl)benzothiazole with Phosphine Ligands

Two novel low molecular weight gelator-driven supramolecular metallogels efficient in antimicrobial activity applications

Recent trends in medicinal applications of mercury based organometallic and coordination compounds

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