New benzimidazole derivative compounds with in vitro fasciolicidal properties
Elora Valderas-García,
Verónica Castilla-Gómez de Agüero,
Laura González del Palacio
et al.
Abstract:Background
Control of the zoonotic food-borne parasite Fasciola hepatica remains a major challenge in humans and livestock. It is estimated that annual economic losses due to fasciolosis can reach US$3.2 billion in agriculture and livestock. Moreover, the wide distribution of drug-resistant parasite populations and the absence of a vaccine threaten sustainable control, reinforcing the need for novel flukicides.
Methods
The present work analyses the… Show more
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