New Azomethine-Azo heterocyclic ligands via cyclization of ester

Synthesis, Characterization and Biological activity study for new hybrid polymers by grafting 1,3,4-triazole and 1,2,4-oxadiazle moieties onto polyvinyl chloride

“…On a microplate reader at 492 nm, the absorbency was determined, the assay was carried out in triplicate. The inhibition rate of cell growth was determined as the following equation (the percentage of cytotoxicity) [31][32][33][34][35][36]:-Cytotoxicity = A-B/A *100 where the optical control density and optical test density are A and B, with an unpaired t-test with GraphPad Prism 6, the data obtained was statically analyzed. The values of the triplicate measurments were described as mean ± SEM [30].…”

“…The finding of this study indicate that the M6 and M7 could be used for medical applications and include a beneficial chemotherapy formulation (figures 1 and 2). The results of these study shows that (M4 and M7) have a good anti-Bacterial activity [31,[36][37] due to their structure that form interaction with wall of cell in selected bacteria which caused high inhibition.…”

Synthesis of Triazole Derivatives Via Multi Components Reaction and Studying of (Organic Characterization, Chromatographic Behavior ,Chem-Physical properties)

“…Triazol, imidazole and thiazole are simplest type of azole derivatives which is five membered heterocyclic compound [2] . Multi components reaction is an important class in synthetic chemistry like mannich reaction , condensation reaction of carbonyl compounds and other types [3][4][5][6] of organic reaction [7][8][9][10][11][12][13] .The first chemist has been prepared organic compounds via multicomponent reaction [14][15][16][17][18][19] was the Strecker synthesis in 1850. The interaction of multi components [20][21][22] ( three components ) occurs in a low reaction rate according to collision theory.…”

Synthesis, Characterization and Thermal Analysis for New Amoxil Ligands

“…According to amoxil chemical structure, it can be used in medicine as well as in chemistry as a starting material in synthetic reactions [1]. One of the important reactions is cyclization [2][3][4][5][6] and already used in the synthesis of several industrial compounds [6][7][8][9][10], relaxant drugs like diazepam and oxazepam [11][12][13][14][15][16][17], different types of heterocyclic compounds [18][19][20][21][22][23][24] and other compounds in different applications [25][26][27][28][29][30][31]. The heterocyclic compounds containing imidazoles and thiazoles plays an important role in the field of medicinal chemistry [32,33].…”