2022
DOI: 10.55003/cast.2022.04.23.007
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New Azo-Schiff Compounds and Metal Complexes Derived from 2-Naphthol Synthesis, Characterization, Spectrophotometric, and Study of Biological Activity

Abstract: This research involved synthesizing two compounds as derivatives of 2-naphthol by the classical method. The azo coupling compound was prepared via diazonium salt of 4-amino acetophenone followed by 2-naphthole. The azo-Schiff molecule was synthesized through condensation of an azo compound with 5-amino salicylic acid in an acidic medium. Using spectrum approaches, the new compounds are characterized (13C-NMR, 1H-NMR, FT-IR). The acid-base characteristics were investigated at various pH levels (0.67-12), and th… Show more

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Cited by 7 publications
(9 citation statements)
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“…The condition can be treated and the kidney can be reversed to normal size and function after the cure and is 4 to 5 times more common in patients with diabetes than in those without diabetes. Chronic [7,8]. Pyelonephritis (CPN), the term chronic pyelonephritis means a persistent renal infection leading to chronic renal lesion and it is associated with bacterial infection , It represents 25% of all renal diseases, Most cases of CPN have been linked to vesico-ureteric reflux and recurrent infections [9,10].…”
Section: Classification Of Pyelonephritismentioning
confidence: 99%
“…The condition can be treated and the kidney can be reversed to normal size and function after the cure and is 4 to 5 times more common in patients with diabetes than in those without diabetes. Chronic [7,8]. Pyelonephritis (CPN), the term chronic pyelonephritis means a persistent renal infection leading to chronic renal lesion and it is associated with bacterial infection , It represents 25% of all renal diseases, Most cases of CPN have been linked to vesico-ureteric reflux and recurrent infections [9,10].…”
Section: Classification Of Pyelonephritismentioning
confidence: 99%
“…Five fresh bacterial colonies were suspended in nutrient broth (0.5 Mc-Ferland standard tubes with 1.5x10 8 CFU per ml) and adjusted accordingly [15]. A streak of suspension was added to Mueller Hinton agar, which was then covered with all antibiotic discs and incubated aerobically at 37°C for 24 hours [16]. The current study used twelve antibiotics for Gram-negative bacteria and ten antibiotics for Grampositive bacteria, based on the diameter of the bacterial growth zone, the Clinical and Laboratory Standards Institute provides guidelines regarding antibiotic susceptibility and resistance [17].…”
Section: Antibiotics Sensitivity Testmentioning
confidence: 99%
“…Culture characteristics, biochemical tests, and the VITEK 2 System are used to diagnose all growing bacterial isolates [14,15]. Two cytokines were detected in serum of all individuals using ELISA technique; IL-6 and IL-33 [16,17].…”
Section: Total Samples Urine Collection Culturing and Serum Markers M...mentioning
confidence: 99%