New approaches in developing medicinal herbs databases

Abstract

Medicinal herbs databases have become a crucial part of organizing new scientific literature generated in medicinal herbs field, as well as new drug discoveries in the information era. The aim of this review was to track the current status of medicinal herbs databases. Search for finding medicinal herbs databases was carried out via Google and PubMed. PubMed was searched for papers introducing medicinal herbs databases by the recruited search strategy. Papers with an active database on the web were included in the review. Google was also searched for medicinal herbs databases. Both retrieved papers and databases were reviewed by the authors. In this review, the current status of 25 medicinal herbs databases was reviewed, and the important characteristics of databases were mentioned. The reviewed databases had a great variety in terms of characteristics and functions. Finally, some recommendations for the efficient development of medicinal herbs databases were suggested. Although contemporary medicinal herbs databases represent much useful information, adding some features to these databases could assist them to have better functionality. This work may not cover all the necessary information, but we hope that our review can provide readers with fundamental concepts, perspectives and suggestions for constructing more useful databases.

Microbial fortification of pharmacological metabolites in medicinal plants

“…Plants present a huge reservoir of secondary metabolites for medicinal usages. Many open-access databases of pharmacological plant metabolites are available, such as the 25 medicinal herbs databases recently reviewed in Fathifar et al (2023) [95] and PubChem (https://pubchem.ncbi.nlm.nih.gov) that is the world’s largest collection of freely accessible chemical information. Due to the technical difficulties in de novo chemical synthesis, extraction from plants remains the most economic strategy for most of the complex PSMs, in addition to using the medicinal plants directly.…”

Databases on aromatic plants

“…For a dataset, whether in a database or attached as additional information to an article, it means that anyone can read, download, copy, distribute, print, search for, and within and re-use all or parts of data that are contained in it (Sorokina and Steinbeck, 2020). Databases on natural products have advantages such as the potential to discover new medicines from nature and collect important information for users so that they can easily browse search, download, and view data on a natural product of interest (Fathifar et al, 2023).…”

SakeraHerbDB Proposing an Integrated Indonesian Traditional Herbal Medicine Database IITHMDB for Madura Islands Herbs

“…Several previous research about Traditional Herbal Medicine Databases had been done, there were New approaches in developing medicinal herbs databases [12], TCMSID: a simplified integrated database for drug discovery from traditional chinese medicine [13], Traditional herbal medicine: overview of research indexed in the scopus database [14], Global Pharmacopoeia Genome Database is an integrated and mineable genomic database for traditional medicines from eight international pharmacopeias [15], HERB: a high-throughput experiment-and reference-guided database of traditional Chinese medicine [16], TCMIO: A Comprehensive Database of Traditional Chinese Medicine on Immuno-Oncology [17], Traditional Herbal Medicine in Mesoamerica: Toward Its Evidence Base for Improving Universal Health Coverage [18], ETM-DB: integrated Ethiopian traditional herbal medicine and phytochemicals database [19], Agraph convolution-based classification model for traditional Vietnamese herbal medicine database anticancer metabolites [20], CEMTDD: Chinese ethnic minority traditional drug herb, chemical, target, and illness database [21], TCMID: traditional Chinese medicine integrative database for herb molecular mechanism analysis [22], Database of Traditional Chinese Medicinal herbs: A bridge between TCM and modern science [23], Structure-Based Computational Screening of a Traditional Herbal Medicine Discovers Embelin, a Cell-Permeable, Small-Molecular Weight XIAP Inhibitor. 3D Structure Database [24] and A 3D Structure Database of Components from Chinese Traditional Medicinal Herbs [25].…”