New approach towards the polyol route to fabricate MFe2O4 magnetic nanoparticles: The use of MCl2 and Fe(acac)3 as chemical precursors

Solano, Eduardo; Yáñez, Ramón; Ricart, Susagna; Ros, Josep

doi:10.1016/j.jmmm.2015.02.002

Cited by 18 publications

(8 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The IONPs displayed a superparamagnetic behaviour at room temperature (RT) as measured by SQUID-VSM between −7 and 7 T at 300 K, with a saturation magnetization of M s = 90 emu/g. This value is consistent with superparamagnetic iron oxide nanoparticles of similar size and obtained by the polyol method 10 , 20 , 21 . This value is slightly smaller than the theoretical magnetization value for bulk magnetite (92–100 emu/g) 22 , 23 , and this is due to a finite size effect: canting of surface spins which are unaligned with the spins present in the rest of the magnetic domain 24 .…”

Section: Resultssupporting

confidence: 89%

Assessing cell-nanoparticle interactions by high content imaging of biocompatible iron oxide nanoparticles as potential contrast agents for magnetic resonance imaging

Hachani

Birchall²,

Lowdell

et al. 2017

Sci Rep

View full text Add to dashboard Cite

Stem cell tracking in cellular therapy and regenerative medicine is an urgent need, superparamagnetic iron oxide nanoparticles (IONPs) could be used as contrast agents in magnetic resonance imaging (MRI) that allows visualization of the implanted cells ensuring they reach the desired sites in vivo. Herein, we report the study of the interaction of 3,4-dihydroxyhydrocinnamic acid (DHCA) functionalized IONPs that have desirable properties for T2 - weighted MRI, with bone marrow-derived primary human mesenchymal stem cells (hMSCs). Using the multiparametric high-content imaging method, we evaluate cell viability, formation of reactive oxygen species, mitochondrial health, as well as cell morphology and determine that the hMSCs are minimally affected after labelling with IONPs. Their cellular uptake is visualized by transmission electron microscopy (TEM) and Prussian Blue staining, and quantified using an iron specific colourimetric method. In vitro and in vivo studies demonstrate that these IONPs are biocompatible and can produce significant contrast enhancement in T2-weighted MRI. Iron oxide nanoparticles are detected in vivo as hypointense regions in the liver up to two weeks post injection using 9.4 T MRI. These DHCA functionalized IONPs are promising contrast agents for stem cell tracking by T2-weighted MRI as they are biocompatible and show no evidence of cytotoxic effects on hMSCs.

show abstract

Section: Resultssupporting

confidence: 89%

Assessing cell-nanoparticle interactions by high content imaging of biocompatible iron oxide nanoparticles as potential contrast agents for magnetic resonance imaging

Hachani

Birchall²,

Lowdell

et al. 2017

Sci Rep

View full text Add to dashboard Cite

show abstract

“…The obtained coercivity values of other ferrites indicated properties between hard and soft, so it is easy to change their magnetization, suggesting their use as magnetic field conductors. Generally, the obtained coercivity values are higher than their corresponding values reported in the literature, 18 , 19 , 24 , 32 − 34 exhibiting the impact of the present synthesis route.…”

Section: Results and Discussioncontrasting

confidence: 66%

“…The magnetization value for CoFe 2 O 4 was found to be lower than that of the bulk one (80 emu/g) 30 and those prepared via other wet methods. 18 , 19 , 24 , 31 − 33 On the other hand, the magnetization values obtained for the other ferrites are also lower than those reported in the literature. 18 , 19 , 24 Generally, this reduction in the magnetization may be attributed to the smaller sizes of the prepared ferrites in comparison with those obtained by other methods, cation redistribution, or may be due to the presence of antiferromagnetic or magnetically dead layers on the ferrite’s surface.…”

Section: Results and Discussionmentioning

confidence: 55%

Structural and Magnetoelectrical Properties of MFe₂O₄ (M = Co, Ni, Cu, Mg, and Zn) Ferrospinels Synthesized via an Egg-White Biotemplate

et al. 2021

View full text Add to dashboard Cite

Nanocrystalline metal ferrites (MFe 2 O 4 , M = Co, Ni, Cu, Mg, and Zn) were successfully synthesized via autocombustion synthesis using egg white. X-ray diffraction (XRD) measurements revealed the crystallization of the entire ferrites either in the tetragonal structure, such as in the case of CuFe 2 O 4 , or cubic spinels such as in other studied ferrites. The Fourier transform infrared spectral study revealed the characteristic vibration bands of ferrites. Compared to other synthesis methods, the observed variation in the obtained structural parameters could be due to the different cation distribution of the prepared ferrites. In agreement with XRD measurements, the transmission electron microscopy images showed agglomerated particles with cubic morphology for all ferrites. On the other hand, CuFe 2 O 4 showed tetragonal morphology. The magnetization values were found to vary with the type of the metal ion, and CoFe 2 O 4 showed the highest one (42.8 emu/g). Generally, the lower magnetization values obtained than those reported in the literature for all studied ferrites could be attributed to the smaller particle sizes or the cation redistribution. The obtained coercivity values are observed to be higher than their related values in the literature, exhibiting the impact of the present synthesis route. Ac-conductivity as a function of temperature and frequency indicated semiconducting properties with the observed change in the conduction mechanism by increasing the temperature. The obtained low dielectric constant values could suggest using the entire ferrites in high-frequency applications such as microwave devices.

show abstract

“…43 The presence of secondary phases was minimized (but not eliminated) by using CuCl 2 -$2H 2 O as a copper source, as recommended by Ros and colleagues. 44 The size distributions are not quite monodisperse, with ratios of the standard deviation over the mean of approx. 20% (by this metric, a value smaller than 10% would be required for a sample to be deemed monodisperse).…”

Section: Synthesismentioning

confidence: 98%

Synthesis, characterization, and evaluation of PEGylated first-row transition metal ferrite nanoparticles as T₂contrast agents for high-field MRI

et al. 2017

View full text Add to dashboard Cite

Poly(ethylene glycol) (PEG)-coated transition metal ferrite (MFe 2 O 4 ; M ¼ Co, Cu, Fe, Mn, Ni, Zn) nanoparticles (NPs) were generated by a one-pot synthetic protocol and found to be small, fairly monodisperse, and superparamagnetic in nature. When evaluated for high-field magnetic resonance imaging, these showed high values of r 2 and r 2 /r 1 at 9.4 T. The well-documented biocompatibility of PEG coatings makes these NPs attractive candidates as T 2 contrast agents for high-field MRI. A systematic comparison of magnetic and relaxivity measurements reveals MnFe 2 O 4 and CoFe 2 O 4 NPs to be superior T 2 MRI contrast agents compared to Fe 3 O 4 NPs.

show abstract

New approach towards the polyol route to fabricate MFe2O4 magnetic nanoparticles: The use of MCl2 and Fe(acac)3 as chemical precursors

Cited by 18 publications

References 32 publications

Assessing cell-nanoparticle interactions by high content imaging of biocompatible iron oxide nanoparticles as potential contrast agents for magnetic resonance imaging

Assessing cell-nanoparticle interactions by high content imaging of biocompatible iron oxide nanoparticles as potential contrast agents for magnetic resonance imaging

Structural and Magnetoelectrical Properties of MFe₂O₄ (M = Co, Ni, Cu, Mg, and Zn) Ferrospinels Synthesized via an Egg-White Biotemplate

Synthesis, characterization, and evaluation of PEGylated first-row transition metal ferrite nanoparticles as T₂contrast agents for high-field MRI

Contact Info

Product

Resources

About

New approach towards the polyol route to fabricate MFe2O4 magnetic nanoparticles: The use of MCl2 and Fe(acac)3 as chemical precursors

Cited by 18 publications

References 32 publications

Assessing cell-nanoparticle interactions by high content imaging of biocompatible iron oxide nanoparticles as potential contrast agents for magnetic resonance imaging

Assessing cell-nanoparticle interactions by high content imaging of biocompatible iron oxide nanoparticles as potential contrast agents for magnetic resonance imaging

Structural and Magnetoelectrical Properties of MFe2O4 (M = Co, Ni, Cu, Mg, and Zn) Ferrospinels Synthesized via an Egg-White Biotemplate

Synthesis, characterization, and evaluation of PEGylated first-row transition metal ferrite nanoparticles as T2contrast agents for high-field MRI

Contact Info

Product

Resources

About

Structural and Magnetoelectrical Properties of MFe₂O₄ (M = Co, Ni, Cu, Mg, and Zn) Ferrospinels Synthesized via an Egg-White Biotemplate

Synthesis, characterization, and evaluation of PEGylated first-row transition metal ferrite nanoparticles as T₂contrast agents for high-field MRI