New Approach for Treatment of Cutaneous Leishnianiasis by Man Nitol

Abstract

The present study was carried outinHaWija District and surrounding villages. Three villages were chosen (Al-Kadhemia,Sader A1-Naher, A1-Ameniea). The high incidence rate of cutaneous leishmaniasis was during the Winter months (December 1996 to March 1997). The total positive cases were 227 ( 111 males and 116 females). The highest incidence rate was among childeren fiom 1-10 years old.
 Intralesional mannitol solution was shown to be more effective ( 93.89% ) than Hypertonic Sodium Chloride 7% (HSCS) ( 87.50% ) but almost identical to pentostam ( 96.20% ). Most of lesions were cured in first and second injection, in all three treated groups but few of them needed the third injection. In all three treated groups, the scar was absent
 or minimum afier healing. None of the control lesions cured-within 6-8 Weeks.
 It is concluded that 20% rnannitol is aneffective local method of treatment for acute cutaneous leishmaniasis. The efficacy of 20% of mannitol is identical to pentostam and greater than 7% “ HSCS”. i

A Demographic and Epidemiological Investigation of Patients Afflicted with Cutaneous Leishmaniasis in The Diyala Government Region of Iraq

“…In addition, the present findings referred to increase the frequency percentage of leishmaniasis infection among Employee compared to those Not-Employee which it can be explained by increased risk of exposure to the vector insect when they be outdoor this agree with Salimi et al [16] who refer that employee and drier and other working people were more infected than unemployed they also refer that males were more infected than female and they explained that the reason for this may be due to the type of cloths. The same findings reported in Iraqi and Arabian previous studied referred to the increasing of males to females' frequency percentage in addition to the high incidence rate of leishmaniasis in Iraqi cities comparing to the neighboring countries [14,17,18,19,20]. The incidence rate was 45/ 10000 in Alhaweja district [14], while it recorded 15, 5.5 and 2.5 per 10000 in Kirkuk, Samara and Tikrit cities respectively [22,23].…”