New approach for fast identification of cyclitols by MALDI‐TOF mass spectrometry

Al-Suod, Hossam; Pomastowski, Paweł; Ligor, Magdalena

doi:10.1002/pca.2764

Cited by 13 publications

(9 citation statements)

References 26 publications

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“…Some components (fructose and glucose) appeared as different isomers in the form of two or three peaks. The peaks of fructose can be identified with α-furanose, β-furanose, and β-pyranose, while the D-glucose peaks are represented by α-pyranose and β-pyranose, as confirmed by other researchers previously [27]. In Figure 3, a heat map combined with a dendrogram is presented for cyclitols (part A) and sugars (part B).…”

Section: The Content Of Sugars and Cyclitols In The Investigated Honesupporting

confidence: 77%

Correlation Study of Honey Regarding their Physicochemical Properties and Sugars and Cyclitols Content

et al. 2019

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Honey is a natural sweetener, with an osmotic effect on microorganisms due to the increased sugar content and low amount of water. Cyclitols are minor constituents of honey. They play a defensive role in plants against unfavorable environmental conditions. Honey's physicochemical properties can vary, resulting in a wide range of colors, flavors, scents, antioxidant activity, dissimilar values of pH, acidity, electrical conductivity, etc. Some literature regarding correlation between honey types is already available, but a comprehensive study displaying an ample evaluation of multifarious aspects is still needed. This study focuses on the correlation between 18 honey types, originating from 10 countries, collected during four years, summarizing a total of 38 samples. A total of 6 physicochemical properties and 18 target components (sugars and cyclitols) were considered as variables. A correlation analysis is presented between the investigated parameters and between honey types, together with the statistical analysis which allowed for observation of the clusters' distribution according with the investigated variables.

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Section: The Content Of Sugars and Cyclitols In The Investigated Honesupporting

confidence: 77%

Correlation Study of Honey Regarding their Physicochemical Properties and Sugars and Cyclitols Content

et al. 2019

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“…As in case of HPLC and CE, a derivatization step is not required, but experimental results proved that the technique is providing poor resolution for some components like sucrose (Pico et al 2015). Three different cyclitols extracted from alfalfa plant were identified using matrix-assisted laser desorption/ionization with time-offlight mass spectrometry (MALDI-TOF-MS); however, the technique is useful and sensitive for identification, but not suitable for quantification (Al-Suod et al 2018b).…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Determination of Cyclitols and Sugars Following a Comprehensive Investigation of 40 Plants

et al. 2019

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Due to the important features of widely unexplored cyclitols, a comprehensive qualitative and quantitative study is needed. Moreover, measuring the possible available amounts of identified components in plant material represents a stringent need, due to their importance in phytomedicine and their use in food. The purpose of this study was to realize an extended investigation mainly of cyclitols, but of sugars and sugar alcohols as well, from natural sources. Thus, 17 target compounds (7 cyclitols and 2 sugar alcohols and 8 sugars) extracted from medicinal and edible plants are reported. All detected components were simultaneous separated in just one chromatographic run, using a single GC column. A number of 52 sources coming from 40 species were studied. Thus, we report 37 new sources of cyclitols. Moreover, almost for all cyclitols, the richest source was not investigated previously. Therefore, the obtained results can represent a valuable material for food, pharmaceutical, medical, or cosmetic industry interested in the use of cyclitols.

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“…Additionally, little is known regarding the elucidation of the fragmentation pathways of these products or the determination of such compounds in real samples. Only a few papers reporting on the application of the MALDI technique for the determination of sugars and cyclitols can be found in the literature [30][31][32][33][34][35].…”

Section: D-glucosementioning

confidence: 99%

New Methodology for the Identification of Metabolites of Saccharides and Cyclitols by Off-Line EC-MALDI-TOF-MS

Sagandykova

Walczak-Skierska

Monedeiro

et al. 2020

IJMS

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A combination of electrochemistry (EC) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (off-line EC-MALDI-TOF-MS) was applied for determination of the studied biologically active compounds (D-glucose, D-fructose, D-galactose, D-pinitol, L-chiro-inositol, and myo-inositol) and their possible electrochemical metabolites. In this work, boron-doped diamond electrode (BDD) was used as a working electrode. MALDI-TOF-MS experiments were carried out (both in positive and negative ion modes and using two matrices) to identify the structures of electrochemical products. This was one of the first applications of the EC system for the generation of electrochemical products produced from saccharides and cyclitols. Moreover, exploratory data analysis approaches (correlation networks, hierarchical cluster analysis, weighted plots) were used in order to present differences/similarities between the obtained spectra, regarding the class of analyzed compounds, ionization modes, and used matrices. This work presents the investigation and comparison of fragmentation patterns of sugars, cyclitols, and their respective products generated through the electrochemistry (EC) process.

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New approach for fast identification of cyclitols by MALDI‐TOF mass spectrometry

Abstract: The obtained results in this study proved that MALDI-TOF-MS is a rapid, sensitive and very powerful tool for identification of cyclitols within plants and has the potential to differentiate between enantiomers.

Cited by 13 publications

References 26 publications

Correlation Study of Honey Regarding their Physicochemical Properties and Sugars and Cyclitols Content

Correlation Study of Honey Regarding their Physicochemical Properties and Sugars and Cyclitols Content

Simultaneous Determination of Cyclitols and Sugars Following a Comprehensive Investigation of 40 Plants

New Methodology for the Identification of Metabolites of Saccharides and Cyclitols by Off-Line EC-MALDI-TOF-MS

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