New Approach for Determination of Macroscopic Binding Constants of Ligands to Macromolecules

Gharibi, Hussein; Safarpour, M.A.; Rafati, Amir Abbas

doi:10.1006/jcis.1998.6041

Cited by 13 publications

(4 citation statements)

References 33 publications

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“…K E could be specified to the software in one of three different ways. It could be input as a combination of binding energy and system temperature, and evaluated via the Metropolis algorithm [11], or from binding constants [12] for use in the Metropolis algorithm, or, as was applied herein, by direct specification using arbitrarily-derived values. We investigated the influence of K E in the range 0.1-98.0% for 10,000 of particle B (L or transferrin mimic) and 500 of particle A (Al) in a lattice volume of 70 3 vertices.…”

Section: The Simulationmentioning

confidence: 99%

A systems biology approach to the blood–aluminium problem: The application and testing of a computational model

Beardmore

Rugg

Exley

2007

Journal of Inorganic Biochemistry

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Section: The Simulationmentioning

confidence: 99%

A systems biology approach to the blood–aluminium problem: The application and testing of a computational model

Beardmore

Rugg

Exley

2007

Journal of Inorganic Biochemistry

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“…In a broad sense, the restricted geometry conditions encompass phenomena such as heterogeneous catalysis, enzymatic catalysis, reactivity in micellar systems and microemulsions, molecular machines, molecular electronics, trapping of substrates by polyelectrolytes, conformational changes of DNA induced by the binding of solutes, and so forth.…”

Section: Introductionmentioning

confidence: 99%

Kinetic Study of the Oxidation of [Ru(NH₃)₅pz]²⁺ by [Co(C₂O₄)₃]³^- in AOT−Oil−Water Microemulsions and in CTACl Micellar Solutions

et al. 2004

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The kinetics of the electron-transfer reaction between pentaaminepyrazine ruthenium(II), [Ru(NH3)5-pz] 2+ , and trisoxalatecobaltate(III), [Co(C2O4)3] 3-, was studied in sodium bis(2-ethylhexyl)sulfosuccinateoil-water microemulsions and in micellar solutions of hexadecyltrimethylammonium chloride. The results can be interpreted by taking as a starting point the pseudophase model. However, the model must be modified according to the characteristics of the reaction media. In this way, two different equations result for this model in the two reaction media studied. The influence of the surface potential on the parameters (equilibrium and rate constants) of the model is shown.

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“…by using a surfactant concentration range between 0.01 and 0.1 mM [165]. Other studies using potentiometric techniques to investigate the surfactant-cyclodextrin hostguest formation can be found [123,124,[166][167][168][169][170][171].…”

Section: Accepted Manuscriptmentioning

confidence: 99%

The formation of host–guest complexes between surfactants and cyclodextrins

Valente

Söderman

2014

Advances in Colloid and Interface Science

178

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Cyclodextrins are able to act as host molecules in supramolecular chemistry with applications ranging from pharmaceutics to detergency. Among guest molecules surfactants play an important role with both fundamental and practical applications. The formation of cyclodextrin/surfactant host-guest compounds leads to an increase in the critical micelle concentration and in the solubility of surfactants. The possibility of changing the balance between several intermolecular forces, and thus allowing the study of, e.g., dehydration and steric hindrance effects upon association, makes surfactants ideal guest molecules for fundamental studies. Therefore, these systems allow for obtaining a deep insight into the host-guest association mechanism. In this paper, we review the influence on the thermodynamic properties of CD-surfactant association by highlighting the effect of different surfactant architectures (single tail, double-tailed, gemini and bolaform), with special emphasis on cationic surfactants. This is complemented with an assessment of the most common analytical techniques used to follow the association process. The applied methods for computation of the association stoichiometry and stability constants are also reviewed and discussed; this is an important point since there are significant discrepancies and scattered data for similar systems in the literature.In general, the surfactant-cyclodextrin association is treated without reference to the kinetics of the process. However, there are several examples where the kinetics of the process can be investigated, in particular those where volumes of the CD cavity and surfactant (either the tail or in special cases the head group) are similar in magnitude.This will also be critically reviewed.

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New Approach for Determination of Macroscopic Binding Constants of Ligands to Macromolecules

Cited by 13 publications

References 33 publications

A systems biology approach to the blood–aluminium problem: The application and testing of a computational model

A systems biology approach to the blood–aluminium problem: The application and testing of a computational model

Kinetic Study of the Oxidation of [Ru(NH₃)₅pz]²⁺ by [Co(C₂O₄)₃]³^- in AOT−Oil−Water Microemulsions and in CTACl Micellar Solutions

The formation of host–guest complexes between surfactants and cyclodextrins

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New Approach for Determination of Macroscopic Binding Constants of Ligands to Macromolecules

Cited by 13 publications

References 33 publications

A systems biology approach to the blood–aluminium problem: The application and testing of a computational model

A systems biology approach to the blood–aluminium problem: The application and testing of a computational model

Kinetic Study of the Oxidation of [Ru(NH3)5pz]2+ by [Co(C2O4)3]3- in AOT−Oil−Water Microemulsions and in CTACl Micellar Solutions

The formation of host–guest complexes between surfactants and cyclodextrins

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About

Kinetic Study of the Oxidation of [Ru(NH₃)₅pz]²⁺ by [Co(C₂O₄)₃]³^- in AOT−Oil−Water Microemulsions and in CTACl Micellar Solutions