New Applications for Bismuth(III) Salts in Organic Synthesis: From Bulk Chemicals to Steroid and Terpene Chemistry

Abstract

Bismuth(III) salts are currently considered efficient and "ecofriendly" reagents and catalysts for the development of new applications in organic synthesis. The preparation of bismuth(III) triflate and its analogues is reviewed as well as some of their applications to the synthesis of bulk chemicals via electrophilic addition and cyclization reactions. The use of bismuth(III) salts in the development of new chemical processes involving steroids and terpenes as substrates is also discussed.

Triterpene sapogenins with oleanene skeleton: chemotypes and biological activities.

“…It should be mentionrd that carbocation rearrangement concept, important for rationalizing diverse biomimetic cyclization pathways, has found some practical application. Thus, lupane -oleanane transformation based on Wagner-Meerwein rearrangement turned out synthetically useful reaction in case of both: betuline and betulinic acid, which are easily available starting materials (Salvador et al, 2012) (Scheme 3).…”