New antimicrobial agents: The synthesis of Schiff base polymers containing transition metals and their characterization and applications

Abstract

A new polymeric Schiff base containing formaldehyde and 2-thiobarbituric acid moieties was synthesized by the condensation of a monomeric Schiff base derived from 2-hydroxyacetophenone and hydrazine. Polymer-metal complexes were also synthesized by the reaction of the polymeric Schiff base with Mn(II), Co(II), Ni(II), Cu(II), and Zn(II) acetate. The polymeric Schiff base and its polymer-metal complexes were characterized with magnetic moment measurements, elemental analyses, and spectral techniques (infrared, 1 H-NMR, and ultraviolet-visible). The thermal behaviors of these coordination polymers were studied by thermogravimetric analysis in a nitrogen atmosphere up to 800 C. The thermal data revealed that all of the polymer-metal complexes showed higher thermal stabilities than the polymeric Schiff base and also ascribed that the Cu(II) polymer-metal complex showed better heat resistant properties than the other polymer-metal complexes. The antimicrobial activity was screened with the agar well diffusion method against various selected microorganisms, and all of the polymer-metal complexes showed good antimicrobial activity. Among all of the complexes, the antimicrobial activity of the Cu(II) polymer-metal complex showed the highest zone of inhibition because of its higher stability constant and may be used in biomedical applications.

New Fluorescent, Thermally Stable and Film Forming Polyimines Containing Naphthyl Rings

“…17,18 These properties make them important candidate for application in solar cells, 19,20 optoelectronic sensors, 21 photo-luminescent devices, 22 aerospace, 23 packaging materials and antifouling paints. 24 The redox activity of the Schiff base polymers was also reported, therefore they can be employed as redox indicators. 25 The polymer blends are also seeking attention in technological fields during last two decades because of their mechanical properties, which can be altered according to desired application.…”

Synthesis and Characterization of New Photoresponsive, Ortho and Para Oriented Azomethine Polymers

“…18 They can act as antimicrobial agents and these are proving interesting, because these are nonvolatile and thermally stable and cannot penetrate through human skin. 19,20 They could protect losses through skin by volatilization. 21,22 The conjugated polyazomethines indicate fluorescence properties, they can be applied in the manufacture of chemical sensors, photoluminescence devices and light emitting diodes.…”

Synthesis, Characterization and Biological Studies of New Linear Thermally Stable Schiff Base Polymers with Flexible Spacers

“…[10][11][12][13] They are used to prepare composite materials having high resistance at high temperatures, thermostablizers, photoresistors, flame resistance materials, and components of electrochemical cells. [14][15][16] The Schiff base polymers demonstrate antimicrobial activity against bacteria, yeast and fungi. 17,18 Thus these can be used for the purification of industrial contaminants from heavy metals and microbiological organisms and are significant for environmental applications.…”